Results 11 to 20 of about 1,505,314 (311)

Interplay of space radiation and microgravity in DNA damage and DNA damage response [PDF]

open access: yes, 2017
In space, multiple unique environmental factors, particularly microgravity and space radiation, pose constant threat to the DNA integrity of living organisms.
Lu, Tao   +4 more
core   +2 more sources

Under the karst: detecting hidden subterranean assemblages using eDNA metabarcoding in the caves of Christmas Island, Australia

open access: yesScientific Reports, 2020
Subterranean ecosystems are understudied and challenging to conventionally survey given the inaccessibility of underground voids and networks. In this study, we conducted a eukaryotic environmental DNA (eDNA) metabarcoding survey across the karst ...
Katrina M. West   +5 more
doaj   +1 more source

Ancient DNA preserved in small bone fragments from the P.W. Lund collection

open access: yesEcology and Evolution, 2021
The Lund collection is one of the oldest subfossil collections in the world. The vast assemblage of subfossils was collected in the 1830s and 1840s by Peter Wilhelm Lund in Lagoa Santa, Brazil, and was shipped to Copenhagen in 1848, where it was stored ...
Frederik V. Seersholm   +5 more
doaj   +1 more source

Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]

open access: yes, 2011
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Cox, SE   +4 more
core   +4 more sources

Attempted DNA extraction from a Rancho La Brea Columbian mammoth (Mammuthus columbi): prospects for ancient DNA from asphalt deposits. [PDF]

open access: yes, 2014
Fossil-bearing asphalt deposits are an understudied and potentially significant source of ancient DNA. Previous attempts to extract DNA from skeletons preserved at the Rancho La Brea tar pits in Los Angeles, California, have proven unsuccessful, but it ...
Farrell, Aisling B   +5 more
core   +1 more source

Using environmental DNA for detection of Batrachochytrium salamandrivorans in natural water [PDF]

open access: yes, 2020
Rapid, early, and reliable detection of invasive pathogenic microorganisms is essential in order to either predict or delineate an outbreak, and monitor appropriate mitigation measures. The chytrid fungus Batrachochytrium salamandrivorans is expanding in
DeJean, Tony   +10 more
core   +2 more sources

Repair, abort, ignore? Strategies for dealing with UV damage [PDF]

open access: yes, 2011
DNA repair is a prominent member of the nuclear transactions triad (replication, transcription, and repair). Sophisticated mechanisms govern the cellular process of decision-making (to repair or not to repair, to proceed with cell cycle or not and ...
Khalil, Hilal S.   +2 more
core   +3 more sources

Sponges as natural environmental DNA samplers [PDF]

open access: yesCurrent Biology, 2019
At a time of unprecedented impacts on marine biodiversity, scientists are rapidly becoming persuaded by the potential of screening large swathes of the oceans through the retrieval, amplification and sequencing of trace DNA fragments left behind by marine organisms; an approach known as 'environmental DNA' (eDNA) [1].
Mariani, Stefano   +3 more
openaire   +4 more sources

Implementing fluorescence enhancement, quenching, and FRET for investigating flap endonuclease 1 enzymatic reaction at the single-molecule level

open access: yesComputational and Structural Biotechnology Journal, 2021
Flap endonuclease 1 (FEN1) is an important component of the intricate molecular machinery for DNA replication and repair. FEN1 is a structure-specific 5′ nuclease that cleaves nascent single-stranded 5′ flaps during the maturation of Okazaki fragments ...
Mohamed A. Sobhy   +5 more
doaj   +1 more source

Metagenomics: DNA sequencing of environmental samples [PDF]

open access: yesNature Reviews Genetics, 2005
Although genomics has classically focused on pure, easy-to-obtain samples, such as microbes that grow readily in culture or large animals and plants, these organisms represent only a fraction of the living or once-living organisms of interest. Many species are difficult to study in isolation because they fail to grow in laboratory culture, depend on ...
Tringe, Susannah Green, Rubin, Edward M.
openaire   +3 more sources

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