Results 41 to 50 of about 796,175 (269)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

COMPARISON BETWEEN DIFFERENT TISSUES USING INNOVATED METHODS IN EXTRACTION OF DNA FOR IDENTIFICATION OF CORPSE IN CASE OF ENVIRONMENTAL DISASTERS, EXPLOSIONS AND FIRES [PDF]

Journal of Environmental Science, 2019
Introduction: Every disaster is unique and involves interplay of different factors and circumstances such as nature of disaster, number of victims and extent of body fragmentation that ultimately challenges the disaster response planning.
Jihan A. Abd Elwahab, Sherien S. Ghaleb, Mostafa H. Ragab   +2 more
doaj   +1 more source

The description of a new brackish water ciliate species from China, Trachelostyla aestuarina n. sp., with a species key and biogeographic investigation for Trachelostyla (Ciliophora, Sporadotrichida)

Frontiers in Marine Science, 2022
The ciliated protists are a diverse group of microbial eukaryotes that play an important role in the functioning of microbial food webs. The genus Trachelostyla Borror, 1972, comprised a few species with a non-twisted distinctly cephalized shape.
Zihui Zhang, Zihui Zhang, Hunter N. Hines, Hongbo Pan, Hongbo Pan, Jiamei Jiang, Jiamei Jiang   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Characterizing the distribution of the critically endangered estuarine pipefish (Syngnathus watermeyeri) across its range using environmental DNA

Environmental DNA, 2023
The effective management of rare and threatened species, especially in areas where population sizes have diminished, relies on knowledge of their population size, threats, and distribution.
Georgia M. Nester, Matthew J. Heydenrych, Tina E. Berry, Zoe Richards, Johan Wasserman, Nicole E. White, Maarten De Brauwer, Mike Bunce, Miwa Takahashi, Louw Claassens   +9 more
doaj   +1 more source

Population Structure, Genetic Diversity, and Conservation Strategies of a Commercially Important Sleeper Fish, Odontobutis potamophilus (Gobiiformes: Odontobutidae) Based on Gene-Capture Data

Frontiers in Genetics, 2022
Odontobutis potamophilus is a popular food fish in China, distributed mainly in the middle and lower reaches of the Yangtze River, where it is a famous delicacy and a newly focused species for aquaculture. The wild populations of O.
Yun Hu, Yun Hu, Hongjie Li, Hongjie Li, Jianhong Xia, Chenhong Li, Chenhong Li   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Towards a Comprehensive DNA Barcode Library of Stenochironomus Kieffer, 1919 (Diptera: Chironomidae) from China

Diversity
The adoption of DNA-based assessments for biodiversity monitoring has been on the rise. However, the effectiveness of DNA-based taxonomic assignments heavily relies on the availability and reliability of DNA barcode libraries. There is growing demand for
Hui Wang, Hai-Feng Xu, Chen-Hong Li, Hai-Xin Zhang, Yan-Ping Zhang, Bing-Jiao Sun, Xiao-Long Lin   +6 more
doaj   +1 more source