Results 51 to 60 of about 796,175 (269)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Coral monitoring in northwest Australia with environmental DNA metabarcoding using a curated reference database for optimized detection

Environmental DNA, 2022
The need for efficient and more accurate ways of monitoring threatened ecosystems is becoming increasingly urgent as climate change intensifies. Coral reefs are an example of an ecosystem in crisis, with widespread declines in coral cover and diversity ...
Laurence Dugal, Luke Thomas, Shaun P. Wilkinson, Zoe T. Richards, Jason B. Alexander, Arne A.S. Adam, W. Jason Kennington, Simon Jarman, Nicole M. Ryan, Michael Bunce, James P. Gilmour   +10 more
doaj   +1 more source

Environmental versus extra‐organismal DNA [PDF]

Molecular Ecology, 2021
Pawlowski, Jan, Apothéloz‐Perret‐Gentil, Laure, Altermatt, Florian   +2 more
openaire   +3 more sources

Analysis of environmental transcriptomes by DNA microarrays

Environmental Microbiology, 2006
Summary In this work we investigated the correlations between global gene expression patterns and environmental parameters in natural ecosystems. We studied the preferential gene expression of the iron oxidizer bacterium Leptospirillum ferrooxidans to adapt its physiology to
Parro-García, Víctor, Moreno-Paz, Mercedes, González-Toril, Elena   +2 more
openaire   +3 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A qPCR Assay for the Threatened Pilbara Olive Python (Liasis olivaceus barroni)

Environmental DNA
The Pilbara olive python (Liasis olivaceus barroni) is endemic to the Pilbara region of Western Australia and listed as threatened. Despite being a priority conservation target, they are difficult to monitor as their cryptic nature complicates ...
Kathryn L. Dawkins, Benjamin L. Heyward, Mahsa Mousavi‐Derazmahalleh, Nicole E. White, Morten E. Allentoft   +4 more
doaj   +1 more source

The effect of tides on nearshore environmental DNA

PeerJ, 2017
Organisms of all kinds leave genetic traces in their environments, and in recent years, sequencing this environmental DNA (eDNA) has become a tractable means of surveying many species using water, air, or soil samples. The technique is beginning to become a core tool for ecologists, environmental scientists, and biologists of many kinds, but the ...
Kelly, Ryan, Gallego, Ramón, Jacobs-Palmer, Emily   +2 more
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Evaluation of Extraction Methods for the Recovery of Vertebrate DNA From Spider Webs

Environmental DNA
Spider webs have recently been recognized as an excellent source of vertebrate eDNA. Here we compare four sample preparation methods and three commercially available DNA extraction kits to optimize vertebrate eDNA recovery. We assessed DNA yield, purity,
Joshua P. Newton, Morten E. Allentoft, Philip W. Bateman, Matthew A. Campbell, Mahsa Mousavi‐Derazmahalleh, Paul Nevill   +5 more
doaj   +1 more source

Response to Brinkmann et al. “Re-assembly of 19th century smallpox vaccine genomes reveals the contemporaneous use of horsepox and horsepox-related viruses in the United States”

Genome Biology, 2020
We thank Brinkmann and colleagues for their correspondence and their further investigation into these American Civil War Era vaccination strains. Here, we summarize the difficulties and caveats of work with ancient DNA.
Ana T. Duggan, Edward C. Holmes, Hendrik N. Poinar   +2 more
doaj   +1 more source