Results 71 to 80 of about 860,536 (318)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

DNA adducts in fish following an oil spill exposure [PDF]

, 2006
On 12 December 1999, one third of the load of the Erika tanker, amounting to about 10,000 t crude oil flowed into sea waters close to the French Atlantic Coast.
Castegnaro, Marcel, Amat-Bronnert, Agnès, Burgeot, Thierry, Pfohl-Leszkowicz, Annie   +3 more
core   +1 more source

Functional hierarchy of PCNA‐interacting motifs in DNA processing enzymes [PDF]

, 2023
Numerous eukaryotic DNA processing enzymes, such as DNA polymerases and ligases, bind the processivity factor PCNA, which acts as a platform to recruit and regulate the binding of enzymes to their DNA substrate.
Hamdan, Samir, Samir M. Hamdan, De Biasio, Alfredo, Alfredo De Biasio   +3 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

, 2005
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Depledge, Michael H., Hagger, Josephine A., Michael H. Depledge, Susan Jobling, Jobling, S, Jobling, Susan, Galloway, Tamara S., Oehlmann, Jörg, Oehlmann, J, Tamara S. Galloway, Hagger, JA, Josephine A. Hagger, Jörg Oehlmann, Depledge, MH, Galloway, TS   +14 more
core   +1 more source

(chytrid fungus), using environmental DNA [PDF]

, 2022
Chytridiomycosis, a primary disease driving widespread and unprecedented amphibian declines, is caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd).
Sibelle Torres Vilaça, Madison J. H. Wikston, Dennis L. Murray, Chris C. Wilson, Chris J. Kyle, Megan Congram, David Lesbarrères, Lynne Beaty   +7 more
core   +1 more source

Characterizing the distribution of the critically endangered estuarine pipefish (Syngnathus watermeyeri) across its range using environmental DNA

Environmental DNA, 2023
The effective management of rare and threatened species, especially in areas where population sizes have diminished, relies on knowledge of their population size, threats, and distribution.
Georgia M. Nester, Matthew J. Heydenrych, Tina E. Berry, Zoe Richards, Johan Wasserman, Nicole E. White, Maarten De Brauwer, Mike Bunce, Miwa Takahashi, Louw Claassens   +9 more
doaj   +1 more source

The description of a new brackish water ciliate species from China, Trachelostyla aestuarina n. sp., with a species key and biogeographic investigation for Trachelostyla (Ciliophora, Sporadotrichida)

Frontiers in Marine Science, 2022
The ciliated protists are a diverse group of microbial eukaryotes that play an important role in the functioning of microbial food webs. The genus Trachelostyla Borror, 1972, comprised a few species with a non-twisted distinctly cephalized shape.
Zihui Zhang, Zihui Zhang, Hunter N. Hines, Hongbo Pan, Hongbo Pan, Jiamei Jiang, Jiamei Jiang   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source