Results 11 to 20 of about 13,167 (137)
Assessing the suitability of mitochondrial and nuclear DNA genetic markers for molecular systematics and species identification of helminths [PDF]
Parasites & Vectors, 2021 Abstract Background Genetic markers are employed widely in molecular studies, and their utility depends on the degree of sequence variation, which dictates the type of application for which they are suited. Consequently, the suitability of a genetic marker for any specific application is complicated by its properties and
Chan, Abigail Hui En +5 more
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Infection by a helminth parasite is associated with changes in
Ecology and Evolution, 2022 AbstractParasites can exert strong selective pressures on their hosts and influence the evolution of host immunity. While several studies have examined the genetic basis for parasite resistance, the role of epigenetics in the immune response to parasites is less understood.
Sarah L. Lundregan +5 more
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Transient expression of DNA and RNA in parasitic helminths by using particle bombardment [PDF]
Proceedings of the National Academy of Sciences, 1999 Parasitic helminths (worms belonging to several metazoan phyla) cause considerable morbidity and mortality in humans. They are an important veterinary problem, and they result in significant economic losses in animal grazing and agriculture.
R E, Davis +5 more
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Paper-Based DNA Reader for Visualized Quantification of Soil-Transmitted Helminth Infections [PDF]
ACS Sensors, 2018 Soil-transmitted helminth (STH) infections are a global health issue affecting nearly one-third of the world's population. As most endemic areas of STH are impoverished countries or regions with limited healthcare resources, the accurate diagnosis of STH requires analytical tools that are not only quantitative, but also portable, inexpensive, and with ...
Alex Guan Wang +5 more
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Scientific Reports, 2022 AbstractNext-generation sequencing technologies have accelerated the pace of helminth DNA metabarcoding research, enabling species detection in bulk community samples. However, finding suitable genetic markers with robust species-level resolution and primers targeting a broad species range among parasitic helminths are some of the challenges faced ...
Chan, AHE +7 more
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Helminth infection impairs the immunogenicity of a Plasmodium falciparum DNA vaccine, but not irradiated sporozoites, in mice [PDF]
Vaccine, 2010 Development of an effective vaccine against malaria remains a priority. However, a significant number of individuals living in tropical areas are also likely to be co-infected with helminths, which are known to adversely affect immune responses to a number of different existing vaccines. Here we compare the response to two prototype malaria vaccines: a
Gregory S, Noland +4 more
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Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts [PDF]
Infectious Agents and Cancer, 2019 Abstract Background Infections classified as group 1 biological carcinogens include the helminthiases caused by Schistosoma haematobium and Opisthorchis viverrini. The molecular mediators underlying the infection with these parasites and cancer remain unclear.
Gouveia, M +5 more
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Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing [PDF]
Frontiers in Genetics, 2019 Abstract Whole genome sequencing is being rapidly applied to the study of helminth genomes, including de novo genome assembly, population genetics, and diagnostic applications. Although late-stage juvenile and adult parasites typically produce sufficient DNA for molecular analyses ...
Stephen R. Doyle +28 more
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The application of recombinant DNA technology to problems of helminth identification
Parasitology, 1986 During the past decade, enormous technological developments have occurred in biology that have led to significant and revolutionary advances. New techniques of DNA cloning, restriction-enzyme analyses and nucleotide sequencing are providing a mass of data concerning the genomes of a wide variety of organisms.
D, Rollinson, T K, Walker, A J, Simpson
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International Journal for Parasitology: Parasites and Wildlife, 2021 Three subspecies of the ringed seal (Pusa hispida) are found in northeastern Europe: P. h. botnica in the Baltic Sea, P. h saimensis in Lake Saimaa in Finland, and P. h. ladogensis in Lake Ladoga in Russia. We investigated the poorly-known cestode helminth communities of these closely related but ecologically divergent subspecies using COI barcode data.
Nyman, Tommi +10 more
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