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Intergenic DNA and the sequence requirements for replication initiation in eukaryotes

Current Opinion in Genetics & Development, 1994
Replication in eukaryotes initiates at many origins per chromosome. The locations of most of these origins appear to be restricted to intergenic spacers. In this review, I propose that the sequence dependence of initiation seen in lower eukaryotes may be a by-product of the small size of intergenic sequences and may not reflect a general requirement of
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Is higher-order structure conserved in eukaryotic ribosomal DNA intergenic spacers?

Journal of Molecular Evolution, 1992
Computer-based structural analysis of the ribosomal DNA intergenic spacer (IGS) from the mosquito Aedes albopictus revealed a potential to form strong and extensive secondary structures throughout a 4.7-kilobase (kb) region. The predicted stability of secondary structures was particularly high within a 3.15-kb region containing 17 tandem 201 base-pair ...
G D, Baldridge, M W, Dalton, A M, Fallon
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Distinctive Sequence Features in Protein Coding Genic Non-coding, and Intergenic Human DNA

Journal of Molecular Biology, 1995
We have studied the behavior of a number of sequence statistics, mostly indicative of protein coding function, in a large set of human clone sequences randomly selected in the course of genome mapping (randomly selected clone sequences), and compared this with the behavior in known sequences containing genes (which we term genic sequences). As expected,
R, Guigó, J W, Fickett
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Transcription of ribosomal DNA intergenic spacer sequences in normal and regenerating rat liver

Biochemical and Biophysical Research Communications, 1991
In regenerating rat liver both the transcriptional activity of the intergenic spacer rDNA promoter and the steady-state abundance of spacer transcripts are increased about 2-fold, as compared to normal liver. These changes are parallel to the observed 2.5-fold increase in regenerating liver of rRNA gene promotor activity and gene promotor transcripts ...
I D, Kalcheva   +2 more
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ORGANIZATION OF THE 5S RIBOSOMAL DNA INTERGENIC SPACER OF APAMEA MONOGLYPHA (LEPIDOPTERA)

Biolohichni systemy, 2023
A significant part of the moth species, representatives of the superfamily Noctuoidea distributed on the territory of Ukraine, are pests of crops, which attracts special attention of researchers. In particular, host plants for the larvae of the Apamea species are cereals. For the correct identification of the pest moth speciesit is necessary to conduct
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Intergenic Recombination, DNA Replication and Synaptonemal Complex Formation in the Drosophila Oocyte

1974
The transition from microbial systems to the higher eukaryotes introduces a different order of time and physical dimensions. For recombination studies the change confers both advantages and disadvantages. The increased complexity of the organism imposes difficulties in isolating meiocytes free of somatic cells and other germ cells for the kinds of ...
Rhoda F. Grell, J. W. Day
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SoDium: Small ORF Detection in Intergenic and Unannotated DNA.

2008
Avner, Stéphane   +3 more
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STRUCTURES IN INTERGENIC DNA OF NON-ALPHA GLOBIN GENES OF MAN

1981
P. Jagadeeswaran   +7 more
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