Results 211 to 220 of about 3,320,596 (325)

From Bioinformatics Analysis to Recombinant Expression: Advancing Public Health with <i>Taenia solium</i> Proteins. [PDF]

Int J Mol Sci
Muñoz J, Guacaneme MCJ, Ovalle-Bracho C, Trujillo JT, Duque-Beltrán S, Arévalo A, Franco-Muñoz C.   +6 more
europepmc   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Journal of Virology, 2003
D. Casimiro, Ling Chen, T. Fu, R. K. Evans, M. Caulfield, M. Davies, Aimin Tang, Minchun Chen, Lingyi Huang, V. Harris, D. Freed, Keith A. Wilson, S. Dubey, De-Min Zhu, Denise K Nawrocki, H. Mach, R. Troutman, L. Isopi, Donna M. Williams, W. Hurni, Zheng Xu, Jeffrey G. Smith, Su Wang, Xu Liu, L. Guan, Romnie Long, W. Trigona, G. Heidecker, H. Perry, N. Persaud, T. Toner, Q. Su, X. Liang, R. Youil, M. Chastain, A. Bett, D. Volkin, E. Emini, J. Shiver   +38 more
semanticscholar   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

Development of convenient potyvirus-based vectors for simultaneous expression of two heterologous proteins in solanaceous plants. [PDF]

BMC Plant Biol
Li N, Deng C, Zhu Y, Qin L, Dai Z, Sun H, Xia C, Cui H, Xiang X.   +8 more
europepmc   +1 more source

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine.

Proceedings of the National Academy of Sciences of the United States of America, 1998
M. Sedegah, T. Jones, M. Kaur, R. Hedstrom, P. Hobart, John A. Tine, S. Hoffman   +6 more
semanticscholar   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

Mechanism of trinucleotide repeat expansion by MutSβ-MutLγ and contraction by FAN1. [PDF]

Nat Commun
Senoussi I, Mengoli V, Cerana A, Rinaldi A, Marco A, Reginato G, Moro SG, Acharya A, Roy M, Jayachandran A, Cannavo E, Ceppi I, Cejka P.   +12 more
europepmc   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Harnessing cytokines: innovative adjuvants for improved veterinary vaccine efficacy. [PDF]

Front Immunol
Yan S, Chen H, Liu Q, Zhang X, Wei Q, Hu C, Chu D, Diao H, Liu S, Chen JL.   +9 more
europepmc   +1 more source