Results 191 to 200 of about 614,049 (312)

Recombinant DNA Advisory Committee: minutes of meeting March 6 and 7, 2003 [PDF]

, 2003
National Institutes of Health [NIH] (United States). Recombinant DNA Advisory Committee [RAC]
core  

Enhancement of RecET-mediated in vivo linear DNA assembly by a xonA mutation. [PDF]

PLoS One
Sawitzke JA, Costantino N, Caballero AC, Hutchinson E, Barenghi A, Thomason LC, Court DL.   +6 more
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Introduction of recombinant DNA-engineered organisms into the environment: key issues [PDF]

, 1987
National Academy of Sciences. Committee on the Introduction of Recombinant DNA-Engineered Organisms into the Environment
core  

Long-term protection following a primary series of hepatitis B vaccine in Alaska Native children and adults. [PDF]

Hepatol Commun
Steinberg J, Blake I, Stevenson T, Wheelock H, Bruden D, Townshend-Bulson L, Klejka J, Peterson M, Cartwright EJ, Drobeniuc J, Scobie HM, Bruce MG, Fischer M, McMahon B.   +13 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Federal Register Announcement of November 21, 1991: Recombinant DNA Research; Action Under the Guidelines [PDF]

, 1992
National Institutes of Health (United States) [NIH]. Recombinant DNA Advisory Committee
core  

Uev1A counteracts oncogenic <i>Ras</i> stimuli in both polyploid and diploid cells. [PDF]

Elife
Zhang Q, Wang Y, Fu X, Wang Z, Zhang Y, Yan L, Wang Y, Yang M, Song D, Zhang R, Zhang H, Wu S, Zhao S.   +12 more
europepmc   +1 more source

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source

National Institutes of Health, Recombinant DNA Advisory Committee (RAC) Meeting June 20-21, 2002. Meeting agenda [PDF]

, 2002
National Institutes of Health [NIH] (United States). Recombinant DNA Advisory Committee [RAC]
core