Results 181 to 190 of about 614,049 (312)

Genetically Modified Lactic Acid Bacteria in the EU Food Chain: Applications, Benefits, and Risk Assessment. [PDF]

Int J Mol Sci
Vacca M, Calabrese FM, Filannino P, De Angelis M.   +3 more
europepmc   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Federal Register Announcement of January 3, 1992: Recombinant DNA Advisory Committee; Meeting [PDF]

, 1992
National Institutes of Health (United States) [NIH]. Recombinant DNA Advisory Committee
core  

Cross-priming amplification strategy-assisted lateral flow immunoassay biosensors for the rapid detection of chicken Eimeria parasites at genus-level and identification of the four most economically important species. [PDF]

Poult Sci
Wang YX, Wu ZX, Wang ZR, Bu YQ, Li S, Li W, Liang Y, Zhu XQ, Liu Q.   +8 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Recombinant DNA Advisory Committee Human Gene Therapy Subcommittee. Minutes of Meeting, December 9 1988 [PDF]

, 1989
National Institutes of Health [NIH] (United States). Recombinant DNA Advisory Committee. Human Gene Therapy Subcommittee.
core  

Importin-9 recognizes the winged-helix fold of ETS transcription factors to mediate nuclear import. [PDF]

Proc Natl Acad Sci U S A
McConville M, Lankford K, Bernardes NE, Walterscheid A, Valadez C, Niesman A, Chook YM, Liszczak G.   +7 more
europepmc   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Assessment of Diagnostic Efficacy of Engineered ESAT-6 Linear Epitopes Based on IFN-γ Secretion in Tuberculosis. [PDF]

Iran J Biotechnol
Jokar A, Mohammadi-Sichani M, Jafarisani M, Beheshti-Maal K, Hosseinzadeh A.   +4 more
europepmc   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source