Results 251 to 260 of about 2,640,580 (326)

Variation in the Content of Three Tandem Repeats of the Human Genome (Ribosomal, Satellite III, and Telomere) in Peripheral Blood Leukocyte DNA of People of Different Ages (5-101 Years). [PDF]

J Aging Res
Ershova ES, Umriukhin PE, Zinchenko RA, Vasilieva TP, Kostyuk SE, Shabalin NY, Salimova TA, Malinovskaya EM, Veiko NN, Kostyuk SV.   +9 more
europepmc   +1 more source

Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Peripheral blood leukocyte telomere length (PBL‐TL) shortening is associated with systemic sclerosis–related interstitial lung disease (SSc‐ILD). However, its association with other organ involvement, disease severity, and survival remains unclear.
Monica M. Yang, Shuo Liu, Michael Wax II, Seoyeon Lee, Sarah French, Paul J. Wolters, Francesco Boin   +6 more
wiley   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

Arthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

Characterization of Longidorus caespiticola (Nematoda: Longidoridae) from the Czech Republic

Helminthologia, 2014
Kumari S.
doaj   +1 more source

Biological Performance and Molecular Mechanisms of Mesyl MicroRNA-Targeted Oligonucleotides in Colorectal Cancer Cells. [PDF]

Int J Mol Sci
Miroshnichenko SK, Patutina OA, Markov AV, Kupryushkin MS, Vlassov VV, Zenkova MA.   +5 more
europepmc   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Decoding protein binding plasticity via integrated deep ribosome display and deep learning. [PDF]

Commun Biol
Tang M, Li J, Li Z, Cui J, Qi H.
europepmc   +1 more source

Adaptive and Biochemical Responses of Dictyosphaerium sp. AM‐2024a to Environmental Conditions and Microplastic Interactions: Synergy of Biofuel Production With Pollution Mitigation

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This study investigates the physiological and biochemical responses of a newly isolated microalgal strain, Dictyosphaerium sp. AM‐2024a, identified through 18S rDNA sequencing, under varying environmental conditions and microplastic (MP) interactions.
Khushboo Iqbal, Arti Mishra, Smitha Mony Sreedharan   +2 more
wiley   +1 more source

Establishment of an imaging-based screening pipeline for the identification of human ribosome biogenesis inhibitors. [PDF]

BMC Biol
Gafko C, Hollandi R, Dörner K, Rosellini M, Zemp I, Horvath P, Kutay U.   +6 more
europepmc   +1 more source

A Review on Quantitative Process Analytical Technology for Continuous Downstream Processing of Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho, Ana Cruz, Cees Haringa, Marcel Ottens, Marieke Klijn   +4 more
wiley   +1 more source