Results 31 to 40 of about 2,640,580 (326)

Ribosomal DNA magnification in Saccharomyces cerevisiae [PDF]

open access: yesJournal of Bacteriology, 1978
Strains monosomic for chromosome I of Saccharomyces cerevisiae contain 25 to 35% fewer rRNA genes than do normal diploid strains. When these strains are repeatedly subcultured, colonies are isolated that have magnified their number of rRNA genes to the diploid amount while remaining monosomic for chromosome I.
D B, Kaback, H O, Halvorson
openaire   +2 more sources

Copy Number of Human Ribosomal Genes With Aging: Unchanged Mean, but Narrowed Range and Decreased Variance in Elderly Group

open access: yesFrontiers in Genetics, 2018
Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA.
Elena M. Malinovskaya   +7 more
doaj   +1 more source

Long-read DNA metabarcoding of ribosomal rRNA in the analysis of fungi from aquatic environments

open access: yesbioRxiv, 2018
DNA metabarcoding is now widely used to study prokaryotic and eukaryotic microbial diversity. Technological constraints have limited most studies to marker lengths of ca. 300-600 bp.
F. Heeger   +8 more
semanticscholar   +1 more source

FabR regulates Salmonella biofilm formation via its direct target FabB [PDF]

open access: yes, 2016
Background: Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA), to have impaired biofilm ...
De Coster, David   +8 more
core   +4 more sources

Ribosomal DNA copy number loss and sequence variation in cancer

open access: yesPLoS Genetics, 2017
Ribosomal DNA is one of the most variable regions in the human genome with respect to copy number. Despite the importance of rDNA for cellular function, we know virtually nothing about what governs its copy number, stability, and sequence in the ...
Baoshan Xu   +9 more
semanticscholar   +1 more source

Phylogenetic analysis of Polystigma and its relationship to Phyllachorales

open access: yesPhytopathologia Mediterranea, 2015
Polystigma amygdalinum, which causes red leaf blotch of almond, is one of the few fungal plant pathogens to remain a taxonomic enigma, primarily because it has resisted cultivation and causes almond leaf blotch only in restricted regions of the world. To
Azadeh HABIBI   +2 more
doaj   +1 more source

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance We demonstrate that ATRX maintains ribosomal DNA (rDNA) heterochromatin formation and stability. ATRX-depleted cells suffer extensive rDNA copy loss, resulting in a reduced ribosomal RNA transcription output and an increased sensitivity to ...
M. Udugama   +14 more
semanticscholar   +1 more source

Unveiling cryptic species diversity of flowering plants: successful biological species identification of Asian Mitella using nuclear ribosomal DNA sequences

open access: yesBMC Evolutionary Biology, 2009
Background Although DNA sequence analysis is becoming a powerful tool for identifying species, it is not easy to assess whether the observed genetic disparity corresponds to reproductive isolation.
Okuyama Yudai, Kato Makoto
doaj   +1 more source

Keeping ribosomal DNA intact: a repeating challenge

open access: yesChromosome Research, 2018
More than half of the human genome consists of repetitive sequences, with the ribosomal DNA (rDNA) representing two of the largest repeats. Repetitive rDNA sequences may form a threat to genomic integrity and cellular homeostasis due to the challenging ...
Daniël O. Warmerdam, R. Wolthuis
semanticscholar   +1 more source

Systematic identification of gene families for use as markers for phylogenetic and phylogeny- driven ecological studies of bacteria and archaea and their major subgroups [PDF]

open access: yes, 2013
With the astonishing rate that the genomic and metagenomic sequence data sets are accumulating, there are many reasons to constrain the data analyses.
Eisen, Jonathan A.   +2 more
core   +4 more sources

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