Results 201 to 210 of about 69,429 (309)

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

First record of Penicilliopsis clavariiformis Solms. on seeds of Diospyros ferrea (Willd.) Bakh. from the Northern Western Ghats, India. [PDF]

Sci Rep
Bagam PH, Magdum AB, Shinde KV, Kumavat SS, Borde MY, Singh SK, Kamble SS, Nimbalkar MS.   +7 more
europepmc   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

Organism-Specific Sequence Motifs Link Ribosomal RNAs to Brain Disorders. [PDF]

Mol Biol Evol
Rigoutsos I, Nersisyan S, Londin E, Nazeraj I, Dong B, Vourekas A, Loher P.   +6 more
europepmc   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Two Native <i>Anagrus</i> spp. (Hymenoptera: Mymaridae) Are Egg Parasitoids of the Invasive Two-Spot Cotton Leafhopper <i>Amrasca biguttula</i> (Ishida) (Hemiptera: Cicadellidae) in Florida, USA. [PDF]

Insects
Revynthi AM, Triapitsyn SV, Velazquez-Hernandez Y, Rugman-Jones PF.   +3 more
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

Full ribosomal RNA gene arrays confirm <i>Marteilia refringens sensu stricto</i> and <i>Marteilia pararefringens</i> as separate species, and assess the validity of current diagnostic regions. [PDF]

Parasitology
Hooper C, Serpin D, Arzul I, Canier L, Bøgwald M, Mortensen S, Aranguren R, Figueras A, Ward GM, Bass D.   +9 more
europepmc   +1 more source

GCN2 in proteostasis: structural logic, signalling networks and disease

The FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei. [PDF]

PLoS One
Kröninger L, Maurya AK, Stiebeling C, Stirba FP, Kim Z, Nowack ECM.   +5 more
europepmc   +1 more source