Results 121 to 130 of about 368,244 (218)

Hydrogen-deuterium exchange points to inter-domain interactions in reverse gyrase that modulate conformational changes in positive DNA supercoiling. [PDF]

J Biol Chem
Mhaindarkar VP, Collin F, Koldewey P, Klostermeier D.   +3 more
europepmc   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Cryptic DNA sequences encode a temperature sensor to regulate mitochondrial suicide during neuronal differentiation. [PDF]

Cell Commun Signal
Vujovic F, Simonian M, Quek LE, Peng KY, Hunter N, Farahani RM.   +5 more
europepmc   +1 more source

Chemically Fueled Systems Chemistry Across Length Scales

Advanced Functional Materials, EarlyView.
Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/functions like spatio‐temporal catalysis, oscillations, optical properties, and perform work.
Brigitte A. K. Kriebisch, Job Boekhoven
wiley   +1 more source

Defense-associated reverse transcriptases define an emerging class of noncanonical DNA-writing systems. [PDF]

Synth Syst Biotechnol
Tong Y.
europepmc   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Preparation of Single-Stranded Phagemid DNA Without Chromosomal DNA Contamination

BioTechniques, 1996
Wei Tang, Jian-Ning Liu, Victor Gurewich
doaj   +1 more source

Stranded short nascent strand sequencing reveals the topology of DNA replication origins in <i>Trypanosoma brucei</i>. [PDF]

Elife
Stanojcic S, Barckmann B, Monsieurs P, Crobu L, George S, Sterkers Y.   +5 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Activity of DNA- and RNA-Guided Prokaryotic Argonautes in Human Mitochondria. [PDF]

Cells
Rimskaya B, Kropocheva E, Ponomareva I, Karchemkina L, Lisitskaya L, Gelfenbein D, Ulashchik E, Shmanai V, Kulbachinskiy A, Mazunin I.   +9 more
europepmc   +1 more source