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Viral connectors for DNA encapsulation

Current Opinion in Biotechnology, 2012
Viral connectors are key components of the life cycle of bacteriophages and other viral systems. They participate in procapsid assembly, and they are instrumental in DNA packaging and release. Connector proteins build hollow cylindrical dodecamers that show an overall morphological similarity among different viral systems including a remarkable ...
Ana, Cuervo, José L, Carrascosa
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On the informational content of viral DNA

Journal of Theoretical Biology, 1983
This paper is concerned primarily with how information is stored in viral DNA. The general problem of defining information content is discussed and a procedure for analysis extended from that of Gatlin (1972) is developed. Long range correlations in base sequences are analyzed for several viral genomes.
G W, Rowe, L E, Trainor
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Viral DNA Synthesis

1991
In 1973, it was first discovered that human hepatitis B virus (HBV) preparations from sera of chronically infected individuals contain an endogenous polymerase activity capable of carrying out a repair reaction on the viral DNA template in the presence of magnesium and nucleotide triphosphates (Kaplan et al. 1973).
C, Seeger, J, Summers, W S, Mason
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Nuclear targeting of viral and non-viral DNA

Expert Opinion on Drug Delivery, 2009
The nuclear envelope presents a major barrier to transgene delivery and expression using a non-viral vector. Virus is capable of overcoming the barrier to deliver their genetic materials efficiently into the nucleus by virtue of the specialized protein components with the unique amino acid sequences recognizing cellular nuclear transport machinery ...
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Initiation of Viral DNA Replication

1988
Publisher Summary This chapter focuses on the mechanisms involved in initiation of animal virus DNA replication. This step is of fundamental importance because it represents the central point of control of the replication process. Two of the best-characterized viruses, adenovirus and SV40, are discussed as examples of viruses that normally multiply ...
T J, Kelly, M S, Wold, J, Li
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Illicit viral DNA

Nature, 1997
Many viruses carry their genetic information in the form of RNA, and with the exception of the retroviruses replicate entirely through RNA intermediates. One such virus is lymphocytic choriomeningitis virus, which has now been caught red-handed in the act of illicit synthesis of DNA — seemingly through the agency of the reverse transcriptase enzyme ...
Robin A. Weiss, Paul Kellam
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Quantitation of bovine papilloma viral DNA in viral-induced tumors

Journal of Virology, 1976
Bovine papilloma virus (BPV) DNA was labeled in vitro under conditions of repair synthesis and subsequently used as a "probe" in DNA-DNA reassociation studies to detect BPV-specific DNA sequences in a viral-induced calf meningioma and hamster fibroma.
W D, Lancaster, C, Olson, W, Meinke
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