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DNA Probes for Viral Diagnosis
1992Great excitement has surrounded the development of molecular hybridization techniques for viruses because of the potential of nucleic acid probes as diagnostic reagents. The need for rapid and accurate viral diagnosis has become particularly pressing with the recent availability of numerous drugs which have been clinically proven as effective in ...
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Serum Hepatitis B Viral DNA in Acute Viral Hepatitis B
Annals of Internal Medicine, 1989Excerpt There is no way to identify which patients with acute hepatitis B infection will recover and which will become chronic carriers.
T L, Fong +4 more
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Quantitation of bovine papilloma viral DNA in viral-induced tumors
Journal of Virology, 1976Bovine papilloma virus (BPV) DNA was labeled in vitro under conditions of repair synthesis and subsequently used as a "probe" in DNA-DNA reassociation studies to detect BPV-specific DNA sequences in a viral-induced calf meningioma and hamster fibroma.
W D, Lancaster, C, Olson, W, Meinke
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Vaccinia DNA: Separation of viral from host cell DNA
Archiv f�r die gesamte Virusforschung, 1967Virus and cell DNA were separated by isopycnic centrifugation after subjecting a mixture to denaturation and reannealing. Virus DNA renatured, while cell DNA retained the density of single-stranded material. This process magnified the originally very small density difference between the two DNA's.
C, Jungwirth, I B, Dawid
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Viral Vaccines and Residual Cellular DNA
Biologicals, 1995The acceptability of viral vaccines manufactured in culture of continuous cell lines opened the way to a new technology of vaccine preparation. The large scale cultivation of continuous cell lines contributed greatly to the improvement of the safety and the consistency of viral vaccines.
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Evolution of viral DNA-dependent RNA polymerases
Virus Genes, 1995The DNA-dependent RNA polymerase (DdRP or RNAP) is an essential enzyme of transcription of replicating systems of prokaryotic and eukaryotic organisms as well as cytoplasmic DNA viruses. DdRPs are complex multisubunit enzymes consisting of 8-14 subunits, including two large subunits and several smaller polypeptides (small subunits). An extensive search
K C, Sonntag, G, Darai
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SARS-CoV-2 viral load and shedding kinetics
Nature Reviews Microbiology, 2022Olha Puhach +2 more
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Antibodies to combat viral infections: development strategies and progress
Nature Reviews Drug Discovery, 2022Giuseppe Pantaleo +2 more
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Viral and host heterogeneity and their effects on the viral life cycle
Nature Reviews Microbiology, 2020Jennifer E Jones +2 more
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