Results 251 to 260 of about 3,750,929 (346)

Circadian clock proteins BMAL1 and CLOCK regulate HSV-1 entry into nerve cells through NECTIN-1. [PDF]

Virol J
Tang J, Pan M, Liu J, Yu G, Wang S, Li F.   +5 more
europepmc   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

Advanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba, Giulia Puliatti, Domenica Donatella Li Puma, Bruno Bandiera, Beatrice Cannata, Maria Elena Marcocci, Nicolina Castagno, Irene Contento, Salvatore Impemba, Mariarosa Scognamiglio, Rocco Di Girolamo, Vincenzo Naddeo, Patrizia Canton, Carmine Capacchione, Laura Sposito, Martina Albini, Francesco Pastore, Silvia Baroni, Alfonso Grassi, Claudio Grassi, Roberto Piacentini   +20 more
wiley   +1 more source

From Viral Infection to Genome Reshaping: The Triggering Role of HPV Integration in Cervical Cancer. [PDF]

Int J Mol Sci
Li J, Li S.
europepmc   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

Advanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost, Annina Stuber, Kongchang Wei, Marine de Lapeyrière, Ke Yang, Valentin Gantenbein, Salvador Pané, Ivan Corbeski, Katharina Maniura‐Weber, Nako Nakatsuka   +9 more
wiley   +1 more source

Camptothecin, a topoisomerase I inhibitor, impedes productive herpes simplex virus type 1 infection. [PDF]

J Virol
Heath JR, Lloyd AE, Kulinski RM, Fromuth DP, Dembowski JA.   +4 more
europepmc   +1 more source

Vertical Nanostructures as Novel Interfaces for Brain Research

Advanced Materials Interfaces, EarlyView.
This review highlights the unique features of vertical nanostructures (nanoneedles, nanostraws, nanopillars, and nanowires) for applications in brain research. Various characteristics of nanostructures, including material selection, fabrication methodology, and geometric designs, are discussed for their specific use in neurite guidance, neuron pinning,
Hao Nguyen Tran, Andrea J. O'Connor, Chennupati Jagadish, Vini Gautam   +3 more
wiley   +1 more source

Heterologous expression of the hypovirus CHV1-EP713 full-length cDNA in Botrytis cinerea: transformation with Agrobacterium tumefaciens and evaluation of changes in the fungal phenotype. [PDF]

Biol Res
Cottet L, Armijo-Godoy G, Castillo A.
europepmc   +1 more source

Fabrication of Multimodal Anion Exchange Membrane for Chromatographic Purification of Full Adeno‐Associated Viral Capsids

Advanced Materials Interfaces, EarlyView.
A novel multi‐modal anion exchange membrane (MMAEX) is successfully fabricated for separating empty and full AAV2 capsids. The functionalized membrane has an average pore size of 0.5 µm and exhibits both charge and hydrophobic functionality. A full capsid recovery of 72.9% at 85.3% purity with gradient elution, or 70.3% recovery at 92.2% purity with ...
Xiaolei Hao, Sumith Ranil Wickramasinghe, Xianghong Qian   +2 more
wiley   +1 more source

Persistent cell-associated HIV-1 RNA in virally suppressed individuals on INSTI-based ART. [PDF]

J Virus Erad
Suzuki K, Gold L, Levert A, Butterly S, Yoo E, Ishida T, Zaunders J, Cysique LA, Brew BJ.   +8 more
europepmc   +1 more source

Antimicrobial Multi‐Assay Evaluation of (Al‐Doped ZnO)‐Ag and TiO2‐Ag Nanocoatings: Impact of Direct and Indirect Mechanisms

Advanced Materials Interfaces, EarlyView.
This work explores the antimicrobial action of AZO‐Ag and TiO2‐Ag nanocoatings on plastic, demonstrating good efficacy against highly‐critical antibiotic‐resistant bacteria, yeast, and virus. A multi‐assay approach is here exploited to inspect the contribution of direct and indirect antimicrobial mechanisms, and potential human toxicity is also ...
Damiano Squitieri, Roberta Vitali, Cecilia Bartoleschi, Giulia Lombardini, Margherita Cacaci, Lorenzo Degli Esposti, Camilla Fusacchia, Skerxho Osmani, Luca Gavioli, Francesca Bugli, Daniele Valerini   +10 more
wiley   +1 more source