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Clinical significance of HPV DNA and EGFR mutations in Egyptian NSCLC. [PDF]
Saeed Mohamed S +7 more
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Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes. [PDF]
Weinheimer AR +12 more
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Lumpy Skin Disease Virus Pathogenesis: Viral Protein Functions and Comparative Insights from Vaccinia Virus. [PDF]
Chen H +5 more
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Adenovirus maturation establishes the transcription competent packaging of its genome. [PDF]
Baumgartl C +6 more
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Viral connectors for DNA encapsulation
Current Opinion in Biotechnology, 2012Viral connectors are key components of the life cycle of bacteriophages and other viral systems. They participate in procapsid assembly, and they are instrumental in DNA packaging and release. Connector proteins build hollow cylindrical dodecamers that show an overall morphological similarity among different viral systems including a remarkable ...
Ana, Cuervo, José L, Carrascosa
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Lipid-Based DNA Therapeutics: Hallmarks of Non-Viral Gene Delivery.
ACS Nano, 2019Gene therapy is a promising strategy for the treatment of monogenic disorders. Non-viral gene delivery systems including lipid-based DNA therapeutics offer the opportunity to deliver an encoding gene sequence specifically to the target tissue and thus ...
Jonas Buck +4 more
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1991
In 1973, it was first discovered that human hepatitis B virus (HBV) preparations from sera of chronically infected individuals contain an endogenous polymerase activity capable of carrying out a repair reaction on the viral DNA template in the presence of magnesium and nucleotide triphosphates (Kaplan et al. 1973).
C, Seeger, J, Summers, W S, Mason
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In 1973, it was first discovered that human hepatitis B virus (HBV) preparations from sera of chronically infected individuals contain an endogenous polymerase activity capable of carrying out a repair reaction on the viral DNA template in the presence of magnesium and nucleotide triphosphates (Kaplan et al. 1973).
C, Seeger, J, Summers, W S, Mason
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On the informational content of viral DNA
Journal of Theoretical Biology, 1983This paper is concerned primarily with how information is stored in viral DNA. The general problem of defining information content is discussed and a procedure for analysis extended from that of Gatlin (1972) is developed. Long range correlations in base sequences are analyzed for several viral genomes.
G W, Rowe, L E, Trainor
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Nuclear targeting of viral and non-viral DNA
Expert Opinion on Drug Delivery, 2009The nuclear envelope presents a major barrier to transgene delivery and expression using a non-viral vector. Virus is capable of overcoming the barrier to deliver their genetic materials efficiently into the nucleus by virtue of the specialized protein components with the unique amino acid sequences recognizing cellular nuclear transport machinery ...
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