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[Progress in clinical research related to viral hepatitis in 2025]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Ding Y, Li Y, Dou XG.
europepmc   +1 more source

[Multi-omics analysis of the relationship between oxidative stress-related gene and prostate cancer]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Ning J, Wang H, Luo S, Jing J, Wang J, Hou H, Liu M.   +6 more
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[Research Progress on Microbiome-Driven Mechanisms and Intervention Strategies for Oral Malodor]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Shang X, Wang Z, Ge S.
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[Eurycomanone inhibits renal ischemia/reperfusion-induced mitochondrial dysfunction and inflammation in mice by binding to STAT3 to inhibit its phosphorylation]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu Z, Mao Z, You D, Wang J, He Y, Yu Y, Wen Z, Fang H, He W.   +8 more
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[High expression of MPP6 predicts poor patient prognosis and promotes malignant biological behaviors of hepatocellular carcinoma cells]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Yu H, Shao Y, Cheng Q, Zhou X, Geng H, Yang Y.   +5 more
europepmc   +1 more source

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肺腺癌长链非编码RNA启动子DNA甲基化的生物信息学分析

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2018
背景与目的 肿瘤相关长链非编码RNA(lincRNA)的异常表达影响癌症的进程, 是肿瘤进展机制研究的热点, 然而其调控机制目前并不清楚。本研究通过生物信息学方法研究肺腺癌lincRNA启动子DNA甲基化水平与基因表达和预后的关系。 方法 从TCGA网站下载肺腺癌Illumina Methylation 450K芯片的全基因组DNA甲基化数据及转录组数据, 分析DNA甲基化在lincRNA基因附近的分布情况及与基因表达的关系; 比较肿瘤组织和癌旁组织DNA甲基化和表达变化。 结果 ...
Wen Zhang, Shao-jun Li, Nan-nan Guo, Yingnan Zhao   +3 more
semanticscholar   +1 more source

DNA甲基化对白血病ABO基因表达的影响

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2016
目的 探讨白血病ABO基因启动子区CpG岛甲基化对ABO基因表达的影响。 方法 以25例白血病患者及20名健康对照者为研究对象，同时以不同浓度去甲基化药物地西他滨处理白血病细胞株K562、HL-60和Jurkat细胞，采用序列特异性引物PCR (PCR-SSP）法检测ABO基因分型，采用实时荧光定量PCR法检测ABO mRNA表达，采用亚硫酸氢盐测序法检测ABO基因启动子区CpG岛甲基化情况。 结果 ①急性淋巴细胞白血病组（10例）和急性髓系白血病组（10例）ABO基因启动子平均甲基化率分别为53.85％
明. M. 邵 Shao, 先萍 Xianping 吕 Lyu, 乾坤 Qiankun 杨 Yang, 伟涛 Weitao 朱 Zhu, 婕. J. 宋 Song, 永奎 Yongkui 孔 Kong, 静. J. 王 Wang, 玲. L. 孙 Sun, 芳. F. 王 Wang   +8 more
semanticscholar   +1 more source