This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide+7 more
wiley +1 more source
The C-terminal zinc finger of the catalytic subunit of DNA polymerase is responsible for direct interaction with the B-subunit [PDF]
Javier Sánchez+4 more
openalex +1 more source
Unwinding-like activity associated with avian retrovirus RNA-directed DNA polymerase
M. Collett, J. Leis, M. Smith, A. Faras
semanticscholar +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao+7 more
wiley +1 more source
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor+10 more
wiley +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
VL-DNA: Enhance DNA Storage Capacity with Variable Payload (Strand) Lengths [PDF]
DNA storage is a promising archival data storage solution to today's big data problem. A DNA storage system encodes and stores digital data with synthetic DNA sequences and decodes DNA sequences back to digital data via sequencing. For efficient target data retrieving, existing Polymerase Chain Reaction PCR based DNA storage systems apply primers as ...
arxiv
Polymerase (DNA directed), delta 2, regulatory subunit 50kDa (POLD2); cytochrome c, somatic (CYCS); metallothionein 1A (MT1A; MTC); aldo-keto reductase family 1, member C3 (AKR1C3); YME1-like 1 (YME1L1); annexin A7 (ANXA7); programmed cell death 4 (PDCD4) [PDF]
openalex +1 more source
Membrane topology of the ArsB protein, the membrane subunit of an anion-translocating ATPase [PDF]
The ars operon of the conjugative R-factor R773 encodes an oxyanion pump that catalyzes extrusion of arsenicals from cells of Escherichia coli. The oxyanion translocation ATPase is composed of two polypeptides, the catalytic ArsA protein and the ...
Rosen, Barry P.+2 more
core +1 more source
Isolation and Characterization of RNA-Directed DNA Polymerase from a B-Type RNA Tumor Virus
A. Dion, A. Vaidya, G. Fout, D. Moore
semanticscholar +1 more source