Results 331 to 340 of about 694,784 (370)

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Development of RNA Aptamers That Inhibit the RNA-Dependent RNA Polymerase Activity of SARS-CoV-2 Strains In Vitro. [PDF]

Int J Mol Sci
Song C, Lee SW.
europepmc   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Small RNA, big defence: Early epigenetic responses to genetic invasion. [PDF]

Quant Plant Biol
Mun S, Kang YJ, Cho J.
europepmc   +1 more source

REV1‑targeting inhibitor JH‑RE‑06 induces ferroptosis via NCOA4‑mediated ferritinophagy in colorectal cancer cells. [PDF]

Oncol Rep
Cheng J, Yang X, Zhao W, Xu J, Hao Y, Xu F.   +5 more
europepmc   +1 more source

Directed Evolution of AtMP2 Peptide: Unlocking Enhanced Antibacterial Potential from <i>Anabas testudineus</i>. [PDF]

Molecules
Lee LT, Ang A, Najm A, Adnan AM, Nordin AM, Mahmood I, Dunkhorol S, Fazry S, Law D.   +8 more
europepmc   +1 more source

Rapid On-Site Detection of <i>Pseudomonas aeruginosa</i> via ecfX-Targeted Loop-Mediated Isothermal Amplification. [PDF]

Biosensors (Basel)
He X, Zeng M, Bai W, Tang Z, Ding J, Chen Z.   +5 more
europepmc   +1 more source

How DNA secondary structures drive replication fork instability.

DNA Repair (Amst)
Sethi A, Fernández-Casañas M, Delpino B, Coster G.   +3 more
europepmc   +1 more source

Plasmodium falciparum DNA repair dynamics reveal unique roles for TLS polymerases and PfRad51 in genome diversification. [PDF]

Nucleic Acids Res
Vishwanatha A, Zhang X, Liu YJ, Leung A, Herring M, Visone J, Chan A, Calhoun S, Deitsch K, Kirkman L.   +9 more
europepmc   +1 more source