Results 101 to 110 of about 26,138 (240)

Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion

Advanced Science, EarlyView.
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen, Zongwei Li, Zhihong Fang, Zou Li, Daoyan Yang, Yuan Li, Shurong Liu, Zhiqiang Liu, Rui Liu, Huan Liu   +9 more
wiley   +1 more source

Polymerase Mu Is a DNA-Directed DNA/RNA Polymerase [PDF]

, 2003
Stephanie A. Nick McElhinny, Dale A. Ramsden   +1 more
openalex   +3 more sources

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

Studies of RNA chain initiation by Escherichia coli RNA polymerase bound to T7 DNA. Direct analysis of the kinetics and extent of RNA chain initiation at T7 promoter A1.

, 1979
William C. Nierman, Michael J. Chamberlin   +1 more
openalex   +1 more source

Normal human placentas contain RNA-directed DNA polymerase activity like that in viruses. [PDF]

, 1978
Jay A. Nelson, J A Leong, Jay A. Levy
openalex   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Extent of Transcription of Mouse Sarcoma-Leukemia Virus by RNA-Directed DNA Polymerase [PDF]

, 1974
A Tavitian, Richard C. Hamelin, Paul Tchen, Beatrix A. Olofsson, M Boiron   +4 more
openalex   +1 more source

DNA-Directed RNA Polymerase III Subunit RPC10 [PDF]

, 2020

openalex   +1 more source

NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis

Advanced Science, EarlyView.
In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu, Kang Ning, Zhaohao Huang, Binyao Chen, Junjie Chen, Yingying Wen, Jian Bu, Han Hong, Qiaorong Chen, Zhuoqi Zhang, Renbing Jia, Wenru Su   +11 more
wiley   +1 more source

tRNATrp as primer for RNA-directed DNA polymerase: structural determinants of function.

, 1979
Barbara Cordell, Ronald Swanstrom, H. M. Goodman, J. Michael Bishop   +3 more
openalex   +1 more source