Results 141 to 150 of about 98,603 (254)

Antibodies to the DNA-directed RNA polymerase II subunit RPB1 occur with highest frequency in centenarians [PDF]

, 2016
Jungwon Han, So-Hyun Park, Dong-Jo Kim, Hyori Kim, Yoon-Ho Choi, Jong‐Hyuk Lee, Sang Chul Park, Junho Chung   +7 more
openalex   +1 more source

RNA‐directed DNA methylation and plant development require an IWR1‐type transcription factor

EMBO Reports, 2010
T. Kanno, E. Bucher, L. Daxinger, B. Huettel, David P. Kreil, Frank Breinig, Marc Lind, M. Schmitt, Stacey A. Simon, Sai Guna Ranjan Gurazada, B. Meyers, Z. Lorković, A. Matzke, M. Matzke   +13 more
semanticscholar   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Seamless and Highly Efficient Site-directed Mutagenesis for Protein, RNA, and Plasmid Engineering. [PDF]

Curr Protoc
Yang XJ.
europepmc   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Translesion DNA polymerases Rev1 and PolH promote LTR-retrotransposon transcription by safeguarding Pol II occupancy in both germline and somatic tissues of Drosophila. [PDF]

Nucleic Acids Res
Li C, Meng Z, Wen Q, Yang W, Xu Y, Lyu Y, Guo Y, Lyu T, Shen D, Dou K.   +9 more
europepmc   +1 more source

DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I.

Proceedings of the National Academy of Sciences of the United States of America, 1995
P. Labhart
semanticscholar   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Mechanism for Nucleotidyl Transfer in LINE-1 ORF2p Revealed by QM/MM Simulations. [PDF]

Int J Mol Sci
Polyakov IV, Miroshnichenko KD, Mulashkina TI, Kulakova AM, Khrenova MG.   +4 more
europepmc   +1 more source

Coupling of transcription and replication machineries in λ DNA replication initiation: evidence for direct interaction of Escherichia coli RNA polymerase and the λO protein [PDF]

, 2010
Anna Szambowska, Marcin Pierechod, Grzegorz Węgrzyn, Monika Glinkowska   +3 more
openalex   +1 more source