Results 161 to 170 of about 98,603 (254)

Relationship between RNA-directed DNA polymerase (reverse transcriptase) from human acute leukemic blood cells and primate type-C viruses.

Proceedings of the National Academy of Sciences of the United States of America, 1974
R. Gallagher, G. Todaro, R. G. Smith, D. Livingston, R. Gallo   +4 more
semanticscholar   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

DNA polymerase α-primase can function as a translesion DNA polymerase. [PDF]

Proc Natl Acad Sci U S A
Mayle R, Georgescu R, O'Donnell ME.
europepmc   +1 more source

Direct cloning of DNA that interacts in vivo with a specific protein: application to RNA polymerase II and sites of pausing in Drosophila [PDF]

, 1998
Andy Law
openalex   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

P3a site-specific and cassette mutagenesis for seamless protein, RNA and plasmid engineering. [PDF]

Genes Cancer
Yang XJ.
europepmc   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Structural insights into the exchange mechanism of a replicative DNA polymerase. [PDF]

Nucleic Acids Res
Feng X, Spiering MM, Ruda de Luna Santos A, Benkovic SJ, Li H.   +4 more
europepmc   +1 more source

RNA-directed DNA polymerase from human leukemic blood cells and from primate type-C virus-producing cells: high- and low-molecular-weight forms with variant biochemical and immunological properties.

, 1975
H. Mondal, Robert E. Gallagher, Robert C. Gallo   +2 more
openalex   +2 more sources

Directed evolution of polymerases to accept nucleotides with nonstandard hydrogen bond patterns.

Biochemistry, 2013
Roberto Laos, R. Shaw, Nicole A. Leal, E. Gaucher, S. Benner   +4 more
semanticscholar   +1 more source