Results 161 to 170 of about 47,098 (282)

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source

RNA-Directed DNA Polymerase and Virus-Induced Leukemia in Mice [PDF]

, 1973
Alan M. Wu, Robert C. Ting, Robert C. Gallo   +2 more
openalex   +1 more source

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling. [PDF]

Nat Commun
Wenson L, Heldin J, Martin M, Erbilgin Y, Salman B, Sundqvist A, Schaal W, Sandbaumhüter FA, Jansson ET, Chen X, Davidsson A, Stenerlöw B, Espinoza JA, Lindström M, Lennartsson J, Spjuth O, Söderberg O.   +16 more
europepmc   +1 more source

Transcriptome‐Wide Association Uncovers LncRNAs Controlling Seed Weight in Soybean

Advanced Science, EarlyView.
This study employs transcriptome‐wide association studies (TWAS) to identify 201 long non‐coding RNAs (lncRNAs) associated with seed weight. Expression quantitative trait locus (eQTL) analysis reveals dynamic and static regulatory variants controlling lncRNA expression across development.
Xiang Wang, Xinyu Jiang, Xiaobo Yuan, Zhipeng Zhou, Zhenwei Zhao, Longfei Wang, Wu Jiao, Wenxue Ye, Qingxin Song   +8 more
wiley   +1 more source

Initiation of DNA synthesis by the avian oncornavirus RNA-directed DNA polymerase: tryptophan tRNA as the major species of primer RNA [PDF]

, 1976
William R. Folk, Anthony J. Faras
openalex   +1 more source

Transgenerational Transmission of Epigenetic Marks During Reproduction in <i>Arabidopsis</i>. [PDF]

Yale J Biol Med
Cheong JJ.
europepmc   +1 more source

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

RNase H and RNA-directed DNA polymerase: associated enzymatic activities of murine mammary tumor virus [PDF]

, 1977
Arnold S. Dion, Charlene J. Williams, Dan H. Moore   +2 more
openalex   +1 more source

Derailing the host machinery to achieve replication: how viroid and viroid-like RNAs successfully copy their genomes in hostile territory. [PDF]

RNA Biol
Kalantidis K, Tselika M, Kallemi P, Bardani E, Kryovrysanaki N, Katsarou K.   +5 more
europepmc   +1 more source

DNA-Directed RNA Polymerase III Subunit RPC2 [PDF]

, 2020
openaire   +1 more source