Results 161 to 170 of about 26,138 (240)
Human placentas contain a specific inhibitor of RNA-directed DNA polymerase. [PDF]
Jay A. Nelson+2 more
openalex +1 more source
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu+6 more
wiley +1 more source
Molecular basis for RNA discrimination by human DNA ligase 1. [PDF]
Tumbale PP+9 more
europepmc +1 more source
Direct observation of DNA rotation during transcription by RNA polymerase
Yoko Harada
openalex +2 more sources
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen+12 more
wiley +1 more source
Reference gene selection for real-time qPCR in European flounder (Platichthys flesus) using organ-specific RNA-seq data. [PDF]
Pomianowski K, Burzyński A.
europepmc +1 more source
Structural and Biochemical Characterization of a Widespread Enterobacterial Peroxidase Encapsulin
Encapsulins are self‐assembling bacterial protein compartments loaded with cargo enzymes. The most abundant encapsulin cargo class are Dye‐decolorizing Peroxidases (DyPs). In this study, we structurally and biochemically characterize a DyP encapsulin found in many enterobacteria.
Natalia C. Ubilla‐Rodriguez+2 more
wiley +1 more source
Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates. [PDF]
Wang H+12 more
europepmc +1 more source
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang+10 more
wiley +1 more source
Discrete measurements of RNA polymerase and reverse transcriptase fidelity reveal evolutionary tuning. [PDF]
Potapov V+11 more
europepmc +1 more source