Results 231 to 240 of about 3,029,744 (275)

Are we there yet with XNA aptamers? [PDF]

RSC Adv
Chaillou S, Thonon S, Reynders S, Lescrinier E, Pinheiro VB.   +4 more
europepmc   +1 more source

Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance. [PDF]

Proc Natl Acad Sci U S A
Longmire P, Chen H, McKinzey DR, Savanagouder M, Kosarek NN, Pesola JM, Bobak CA, Bosco G, Goodrum F, Coen DM.   +9 more
europepmc   +1 more source

Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase. [PDF]

Science
Deng P, Lee H, Armijo C, Wang H, Gao A.
europepmc   +1 more source

DNA-Directed DNA Polymerase Activity in Oncogenic RNA Viruses

Nature, 1970
Besides having RNA-dependent DNA polymerase activity, oncogenic RNA viruses possess a DNA-directed DNA polymerase which is distinguished from previously described enzymes of this type in preferring double-stranded DNA as template and yielding a principally double-stranded product.
A Burny, S Spiegelman
exaly   +4 more sources

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The DNA-directed RNA polymerases of soybean

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
Abstract Four cellular RNA polymerases have been partially purified from hypocotyls of soybean ( Glycine max ). Enzyme isolation from nuclear preparations indicate the DEAE polymerases I and II are localized within the nucleus. Inhibitor studies showed that DEAE polymerase II was preferentially inhibited by α-amanitin, DEAE peaks III and IV were ...
P A, Horgen, J L, Key
openaire   +3 more sources

Improved prediction of prognosis and therapy response for lung adenocarcinoma after identification of DNA-directed RNA polymerase-associated lncRNAs

Journal of Cancer Research and Clinical Oncology, 2023
DNA-directed RNA polymerase (DDRP) related genes and long non-coding RNAs (lncRNAs) play an important role in the development of lung adenocarcinoma (LUAD), the leading cause of cancer-related death worldwide. Therefore, we aimed to construct a DDRP-associated lncRNA model to predict the prognosis of LUAD and to evaluate its sensitivity to ...
Jiaao, Yu, Liqiang, Lan, Caixin, Liu, Xiao, Zhu   +3 more
openaire   +2 more sources

Recognition of Threosyl Nucleotides by DNA and RNA Polymerases. [PDF]

Nucleic Acids Research, 2003
Alpha-L-threose nucleic acids (TNA) are potentially natural nucleic acids that could have acted as an evolutionary alternative to RNA. We determined whether DNA or RNA polymerases could recognize phosphorylated threosyl nucleosides.
Jef Rozenski, Piet Herdewijn, Karen Vastmans   +2 more
exaly   +2 more sources

Effect of granaticin on the activity of DNA-directed RNA polymerase fromStreptomyces granaticolor

Folia Microbiologica, 1989
DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.
J, Smardová, J, Spízek, J, Stastná, M, Klégr   +3 more
openaire   +2 more sources

On the Binding of Rifampicin to the DNA‐Directed RNA Polymerase from Escherichia coli

European Journal of Biochemistry, 1973
The capacity of RNA polymerase to bind the antibiotic rifampicin is rather sensitive to conditions which lead to conformational changes in the enzyme. Repeated freezing and thawing in 1 M LiCl as well as treatment with guanidinium chloride destroys the binding affinity of the enzyme for the inhibitor. Similarly rifampicin does not associate with any of
U I, Lill, G R, Hartmann
openaire   +2 more sources