Results 91 to 100 of about 7,795,985 (403)
Scientific Reports, 2021 Regression models are often used to predict age of an individual based on methylation patterns. Artificial neural network (ANN) however was recently shown to be more accurate for age prediction.
Zhonghui Thong +5 more
doaj +1 more source
A universal framework to efficiently share material and process resources in the DNA construction world [PDF]
arXiv, 2021 DNA constructs and their annotated sequence maps have been rapidly accumulating with the advancement of DNA cloning, synthesis, and assembly methods. Such a resource has the potential to be optimally utilized in an autonomous DNA building platform. However, most DNA design processes today remain manually operated with the assistance of graphical user ...
arxiv
Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers [PDF]
, 2014 Background: DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a serine threonine kinase belonging to the PIKK family (phosphoinositide 3-kinase-like-family of protein kinase), is a critical component of the non-homologous end joining (NHEJ ...
AC Wolff +41 more
core +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Temperature dependence of circular DNA topological states [PDF]
PHYSICAL REVIEW E 79, 041926 (2009), 2009 Circular double stranded DNA has different topological states which are defined by their linking numbers. Equilibrium distribution of linking numbers can be obtained by closing a linear DNA into a circle by ligase. Using Monte Carlo simulation, we predict the temperature dependence of the linking number distribution of small circular DNAs.
arxiv +1 more source
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Reentrant behavior of divalent counterion mediated DNA-DNA electrostatic interaction [PDF]
Phys. Rev. Lett. 105 (2010) 248101, 2009 The problem of DNA-DNA interaction mediated by divalent counterions is studied using computer simulation. Although divalent counterions cannot condense free DNA molecules in solution, we show that if DNA configurational entropy is restricted, divalent counterions can cause DNA reentrant condensation similar to that caused by tri- or tetra-valent ...
arxiv +1 more source
Biological Identifications Through DNA Barcodes
, 2012 Although much biological research depends upon species diagnoses, taxonomic expertise is collapsing. We are convinced that the sole prospect for a sustainable identification capability lies in the construction of systems that employ DNA sequences as ...
H. Ramadan, N. Baeshen
semanticscholar +1 more source
Biological identifications through DNA barcodes
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2003 Although much biological research depends upon species diagnoses, taxonomic expertise is collapsing. We are convinced that the sole prospect for a sustainable identification capability lies in the construction of systems that employ DNA sequences as ...
P. Hebert +3 more
semanticscholar +1 more source
Phylogeny and DNA-DNA hybridization. [PDF]
Molecular Biology and Evolution, 1986 Resolving the phylogeny of the hominoid primates is a test case for molecular systematic methods because, by most genetic measures, humans, chimpanzees, and gorillas are very closely related. Recently, Sibley and Ahlquist (1984) applied DNADNA hybridization techniques to infer the hominoid phylogenetic tree with humans and chimpanzees closest ...
Temple F. Smith, Maryellen Ruvolo
openaire +3 more sources