Results 81 to 90 of about 4,554,738 (310)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Admission Notification 2015-16

, 2015
Admission notification for A.Y.
DNA
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Classified for SoA 2015-16

, 2015
Vacancy notification for School of Architecture A.Y.
DNA
core  

REPAIRtoire--a database of DNA repair pathways. [PDF]

, 2010
REPAIRtoire is the first comprehensive database resource for systems biology of DNA damage and repair. The database collects and organizes the following types of information: (i) DNA damage linked to environmental mutagenic and cytotoxic agents, (ii ...
Rother, Kristian, K. Poleszak, Papaj, Grzegorz, E. Osinska, Bujnicki, Janusz M, Lesiak, Justyna, G. Papaj, J. Lesiak, Milanowska, Kaja, J. Krwawicz, Kosinski, Jan, K. Rother, Krwawicz, Joanna, K. Milanowska, Poleszak, Katarzyna, Osinska, Ewelina, J. Kosinski, J. M. Bujnicki   +17 more
core   +1 more source

DNA barcoding, forensics, and application of DNA chip technology

, 2010
Among the 1,121 recognized fish species in Korean waters, approximately 9% (12 Elasmobranchii and 88 Actinopterygii species) have been barcoded with regards to the COI sequences. The DNA barcodes have been used for investigation of correctness in species
이유철, 이강현, 김고은, 김성, 강미혜, Habib, 배세진, Seung Yong Hwang, 정다금, 오지나, 이윤호   +10 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Metabolic engineering with ATP-citrate lyase and nitrogen source supplementation improves itaconic acid production in Aspergillus niger

Biotechnology for Biofuels, 2019
Background Bio-based production of organic acids promises to be an attractive alternative for the chemicals industry to substitute petrochemicals as building-block chemicals.
Abeer H. Hossain, Roy van Gerven, Karin M. Overkamp, Peter S. Lübeck, Hatice Taşpınar, Mustafa Türker, Peter J. Punt   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

«Junk DNA»: «DNA zabor» ala «DNA txatar»?

EKAIA Euskal Herriko Unibertsitateko Zientzia eta Teknologia Aldizkaria, 2013
Funtzio ezagunik edo argirik ez duen genomaren zatia DNA zabor bezala ezagutzen da. DNA zaborra eratzen duten osagaiak gehiago ikertzen goazen heinean, osagai hauek genometan izan dezaketen garrantzia ere azaleratzen doa. Era berean, hain garrantzia handia egozten ez dioten aurkikuntzak ere egin dira.
openaire   +2 more sources