Results 231 to 240 of about 6,548,876 (337)

Junk DNA: "DNA zabor" ala "DNA txatar"?

open access: yes, 2013
Funtzio ezagunik edo argirik ez duen genomaren zatia DNA zabor bezala ezagutzen da. DNA zaborra eratzen duten osagaiak gehiago ikertzen goazen heinean, osagai hauek genometan izan dezaketen garrantzia ere azaleratzen doa. Era berean, hain garrantzia handia egozten ez dioten aurkikuntzak ere egin dira.
openaire   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

P745: High-fidelity whole genome sequencing of FFPE tumor-derived nucleic acids stored at ambient temperature

open access: yesGenetics in Medicine Open
Farnoosh Abbas-Aghababazadeh   +7 more
doaj   +1 more source

THE NEGATIVE CONTROL MECHANISM FOR E. coli DNA REPLICATION [PDF]

open access: green, 1969
Barbara Hatch Rosenberg   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Chemical autoligation with phosphorothioate- and sulfonamide-terminated DNA via intramolecular cross-activation. [PDF]

open access: yesCommun Chem
Yokoe H   +7 more
europepmc   +1 more source

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