Results 281 to 290 of about 8,718,410 (331)

Hierarchy of Hydrophobic and Electrostatic Interactions in DNA-Membrane Phase Selectivity. [PDF]

ACS Appl Mater Interfaces
Wong SH, Lou Y, Chen Y, Morzy D, Bastings MMC.   +4 more
europepmc   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Mechanistic models of asymmetric hand-over-hand translocation and nucleosome navigation by CMG helicase. [PDF]

Nat Commun
Nagae F, Murata Y, Yamauchi M, Takada S, Terakawa T.   +4 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Transomic analysis reveals DNA methylation and transcription factor roles in obese liver protein expression. [PDF]

NPJ Syst Biol Appl
Maehara H, Hatano A, Shirai M, Kokaji T, Suzuki Y, Matsumoto M, Egami R, Kubota H, Araki H, Miura F, Ito T, Kuroda S.   +11 more
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Decitabine-mediated DNA methylation dynamics at pericentromeric satellite 2 repeats. [PDF]

BMC Cancer
Sordini E, Ciurlia E, Zanella A, Fogliardi B, Lame D, Poloni A, Amatori S, Fanelli M.   +7 more
europepmc   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Proteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms. [PDF]

Cell Death Discov
Kim N, Kim M, Jeong E, Yeo JE, Kim BG, Myung K, Schärer OD, Lee KY.   +7 more
europepmc   +1 more source