Results 211 to 220 of about 108,337 (292)

Systematic Evaluation of Electrophile Reactivity and Stability for Covalent DNA‐Encoded Libraries

Helvetica Chimica Acta, EarlyView.
To facilitate the design and construction of covalent DNA‐encoded libraries, a set of 59 electrophilic compounds from six different classes was systematically investigated for DNA‐conjugatability, S‐ and N‐nucleophile reactivity, as well as on‐DNA stability.
Johanna Puff, Giulia Assoni, Jiannan Zhao, Qi Zhang, Zhongyao Ma, Huan Liu, Weiren Cui, Alexander L. Satz, Wenji Su, Letian Kuai, Andreas Gloger, Jörg Scheuermann   +11 more
wiley   +1 more source

A DNA barcode library for Culex mosquitoes (Diptera: Culicidae) of South America with the description of two cryptic species of subgenus Melanoconion. [PDF]

PLoS One
Talaga S, Guidez A, de Thoisy B, Lavergne A, Carinci R, Gaborit P, Issaly J, Dusfour I, Duchemin JB.   +8 more
europepmc   +1 more source

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Integrative use of DNA barcode and morphology reveal high level of diversity in the ornamental fish on the lower Amazon basin. [PDF]

PLoS One
de Freitas EA, Dos Santos DB, Moraes Ferreira CS, Silva-Oliveira C, Evangelista-Gomes GF, Veneza IB.   +5 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, EarlyView.
What's New? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Marine catfishes (Ariidae-Siluriformes) from the Coastal Amazon: mitochondrial DNA barcode for a recent diversification group? [PDF]

PeerJ
Lutz Í, Martins T, Santana P, Ferreira C, Miranda J, Matos S, Muhala V, Sampaio I, Vallinoto M, Evangelista-Gomes G.   +9 more
europepmc   +1 more source

Arbuscular mycorrhizal fungal community abundance, functions, and symbiotic interactions revealed by root metatranscriptomes

iMetaOmics, EarlyView.
Paradigm shift: PCR‐free methods reveal 6–15‐fold higher arbuscular mycorrhizal (AM) fungal abundance than metabarcoding, exposing systematic underestimation across decades of research. Predictive power: AM fungal abundance serves as a community‐level trait that predicts crop yield under drought conditions.
Peilin Chen, John W. Taylor, Cheng Gao
wiley   +1 more source

Rust HUBB: DNA barcode-based identification of Pucciniales. [PDF]

IMA Fungus
Kaishian P, Layug CRK, Anderson M, Berg DR, Aime MC.   +4 more
europepmc   +1 more source

Review marcatori a DNA per ispezione [PDF]

, 2012
Guarniero, Ilaria
core  

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

iMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian, Liujing Huang, Yifan Liu, Xudong Mai, Yanbo Cheng, Bingdong Liu, Yixin Chen, Liwei Xie   +7 more
wiley   +1 more source