Results 61 to 70 of about 107,065 (275)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Towards a Comprehensive DNA Barcode Library of Stenochironomus Kieffer, 1919 (Diptera: Chironomidae) from China

open access: yesDiversity
The adoption of DNA-based assessments for biodiversity monitoring has been on the rise. However, the effectiveness of DNA-based taxonomic assignments heavily relies on the availability and reliability of DNA barcode libraries. There is growing demand for
Hui Wang   +6 more
doaj   +1 more source

Phenological Attributes and Phylogenetic Relationships of \u3ci\u3eRhagoletis Juniperina\u3c/i\u3e Marcovitch (Diptera: Tephritidae) in the Great Lakes Region [PDF]

open access: yes, 2018
Rhagoletis juniperina Marcovitch (Diptera: Tephritidae) infests Eastern Red Cedar (Juniperus virginiana L.) and other North American junipers. While several Rhagoletis species are of interest as orchard crop pests (apple maggot, blueberry maggot, cherry ...
Frayer, Megan   +3 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Barcode DNA Tanaman Leilem (Clerodendrum Minahassae L.) Berdasarkan Gen MatK [PDF]

open access: yes, 2014
Gen matK merupakan gen pengkode protein maturaseK yang terdapat pada kloroplas tumbuhan. Penelitian ini bertujuan untuk menentukan urutan nukleotida dari barcode DNA tanaman leilem (Clerodendrum minahassae L.) berdasarkan gen matK.
Kalangi, C. (Cindy)   +2 more
core   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Probing the connectivity of neural circuits at single-neuron resolution using high-throughput DNA sequencing [PDF]

open access: yes, 2011
There is growing excitement in determining the complete connectivity diagram of the brain—the "connectome". So far, the complete connectome has been established for only one organism, C.
Alex Koulakov   +6 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

DNA Barcode Gap Analysis for Multiple Marker Genes for Phytoplankton Species Biodiversity in Mediterranean Aquatic Ecosystems

open access: yesBiology, 2022
The implementation of DNA metabarcoding and environmental DNA (eDNA) to the biodiversity assessment and biomonitoring of aquatic ecosystems has great potential worldwide.
Eftychia Tzafesta   +5 more
doaj   +1 more source

DNA-BAR: distinguisher selection for DNA barcoding [PDF]

open access: yesBioinformatics, 2005
DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism.
B, DasGupta   +3 more
openaire   +2 more sources

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