Results 141 to 150 of about 90,456 (335)

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong   +19 more
wiley   +1 more source

Comparative performance of the 16S rRNA gene in DNA barcoding of amphibians. [PDF]

open access: gold, 2005
Miguel Vences   +4 more
openalex   +1 more source

Polyadenylation Complex CFII Recognizes Downstream Cis‐element for Pre‐mRNA Polyadenylation Through Interaction with an RNA‐Binding Protein in Arabidopsis

open access: yesAdvanced Science, EarlyView.
This study investigates the cis‐element in pre‐mRNA recognized by the polyadenylation CFII complex. It elucidates how the CFII complex recognizes the consensus cis‐element downstream of the poly(A) site for pre‐mRNA alternative polyadenylation. This comprehensive research provides novel insights into the interaction between 3′ end processing complexes ...
Ying Cao   +13 more
wiley   +1 more source

Use of DNA barcodes to identify flowering plants [PDF]

open access: green, 2005
W. John Kress   +4 more
openalex   +1 more source

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

open access: yesAdvanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh   +11 more
wiley   +1 more source

Land plants and DNA barcodes: short-term and long-term goals [PDF]

open access: green, 2005
Mark W. Chase   +6 more
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Defining operational taxonomic units using DNA barcode data [PDF]

open access: green, 2005
Mark Blaxter   +6 more
openalex   +1 more source

Highly Ordered DNA Framework Interface Enables Efficient Enzymatic Oligonucleotide Synthesis

open access: yesAdvanced Science, EarlyView.
Tetrahedral DNA nanostructures (TDN) ‐based nanoscopic interface provides ordered upright orientation and optimal spacing for initiator primers, enhancing enzyme accessibility in interfacial enzymatic oligonucleotide synthesis (EOS). Notably, efficient TDN‐based EOS is employed for DNA information storage by synthesizing a 60‐nucletide DNA fragment ...
Kunjie Li   +9 more
wiley   +1 more source

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