Results 31 to 40 of about 40,802 (260)
The Promise of DNA Barcoding for Taxonomy [PDF]
Systematic Biology, 2005 DNA barcoding is a novel system designed to provide rapid, accurate, and automatable species identifications by using short, standardized gene regions as internal species tags. As a consequence, it will make the Linnaean taxonomic system more accessible, with benefits to ecologists, conservationists, and the diversity of agencies charged with the ...
Paul D N, Hebert, T Ryan, Gregory
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Discover SustainabilityGreen spaces and natural attractions are critical assets in promoting sustainable tourism, particularly in ecologically diverse regions such as South Africa.
Enioluwa Jonathan Ijatuyi +2 more
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Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation
Advanced Materials, EarlyView.LipidXplorer is a novel microfluidic platform which enables rapid navigation of lipid particle design space for high‐resolution phase mapping, lipid nanoparticle optimization, membrane biophysics, and functional nanomaterial discovery. It combines programmable composition control, continuous nanoparticle formation, and automated well‐plate collection ...
Bradley Diggines +10 more
wiley +1 more source
DNA barcoding and the renaissance of taxonomy [PDF]
Proceedings of the National Academy of Sciences, 2007 How limited (or not) is the dietary range of an animal species? How does that host specificity plot across major lineages of organisms? How does that affect the structure of ecological communities? These are major questions in ecology, especially for invertebrates, where they have major implications for academic questions, such as how many species of ...
openaire +3 more sources
DNA barcoding in herbal medicine: Retrospective and prospective
Journal of Pharmaceutical Analysis, 2023 DNA barcoding has been widely used for herb identification in recent decades, enabling safety and innovation in the field of herbal medicine. In this article, we summarize recent progress in DNA barcoding for herbal medicine to provide ideas for the ...
Shilin Chen +6 more
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Advanced Science, EarlyView.We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel +16 more
wiley +1 more source
MoleculesThunbergia laurifolia Lindl. is a plant known for its promising biological activity, including antioxidant and anti-inflammatory activities, and a rich source of rosmarinic acid (RA). The extraction of T.
Krittima Kriengsaksri +5 more
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