Results 41 to 50 of about 73,396 (304)

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. [PDF]

, 2016
High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemokine ...
Baechler, Emily C, Balboni, Imelda M, Diep, Vivian K, Haddon, D James, Hall, Drew A, Lee, Jung-Rok, Petri, Michelle, Price, Jordan V, Utz, Paul J, Wand, Hannah E, Wang, Shan X   +10 more
core   +2 more sources

Effect of Graphene Oxide Modification on a DNA Biosensor Developed for the Detection of Methylated DNA Associated with Cancer

Proceedings, 2019
Methylated DNA is a covalent post-translational modification, which plays a crucial role in pathological and physiological processes including several diseases, such as cardiovascular disease, diabetes or cancer.
Eliska Sedlackova, Lukas Richtera, Pedro Estrela, Vojtech Adam   +3 more
doaj   +1 more source

Electrochemical DNA biosensor for the detection of trichoderma harzianum based on agold electrode modified with a composite membrane made from an ionic liquid, ZnO nanoparticles and chitosan, and by using acridine orange as a redox indicator. [PDF]

, 2010
An electrochemical DNA biosensor was developed that is based on a gold electrode modified with a nanocomposite membrane made from an ionic liquid, ZnO nanoparticles and chitosan. A single-stranded DNA probe was immobilized on this electrode.
Abu Bakar, Fatimah, Salleh, Abu Bakar, Siddiquee, Shafiquzzaman, Tan, Soon Guan, Yusof, Nor Azah   +4 more
core   +1 more source

Development of a Highly Sensitive SPR Biosensor for BCR–ABL Gene Sequence Detection Using a Novel Gold Nanoparticle–Enhanced Sandwich Assay Format

Micromachines
SPR (surface plasmon resonance) biosensor–based analytical methods enable rapid, straightforward, and cost-effective detection of DNA oligonucleotides. However, the detection limits of currently available SPR biosensors for BCR–ABL gene oligonucleotides ...
Maksym S. Sobolevskyi, Andrii M. Lopatynskyi, Anton V. Samoylov, Glib V. Dorozinsky, Oleksandr M. Lyapin, Roman V. Khrystosenko, Volodymyr I. Chegel, Viktoriya M. Pyeshkova, Abdelhamid Errachid, Sergei V. Dzyadevych, Oleksandr O. Soldatkin   +10 more
doaj   +1 more source

Electrochemical Aptasensor for Detection of Dopamine [PDF]

, 2020
This work presents a proof of concept of a novel, simple, and sensitive method of detection of dopamine, a neurotransmitter within the human brain. We propose a simple electrochemical method for the detection of dopamine using a dopamine-specific aptamer
Abu-Ali, Hisham, Davis, Frank, Nabok, Alexei, Ozkaya, Cansu, Walch, Nik   +4 more
core   +1 more source

Towards HIV Detection: Novel Poly(propylene imine) Dendrimer-Streptavidin Platform for Electrochemical DNA and gp120 Aptamer Biosensors

International Journal of Electrochemical Science, 2014
The detection of sequence - specific DNA and HIV glycoprotein 120 (gp120) based on novel generation 4 poly(propylene imine) dendrimer/streptavidin platform is reported.
Suru V. John, Lia S. Rotherham, Makobetsa Khati, Bhekie B. Mamba, Omotayo A. Arotiba   +4 more
doaj   +1 more source

Nanocrystalline diamond film for biosensor applications [PDF]

, 2010
In this study, we have developed a novel capacitive biosensor based oil interdigitated gold nanodiamond (GID-NCD) electrode for detection of C-reactive protein (CRP) antigen.
Davidson, Jımmy L., Davidson, Jimmy L., Gurbuz, Yasar, Gürbüz, Yaşar, Howell, Mick, Kang, Weng P., Qureshi, Anjum   +6 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

H2O2 biosensor consisted of hemoglobin-DNA conjugate on nanoporous gold thin film electrode with electrochemical signal enhancement

Nano Convergence, 2019
In this research, we developed electrochemical biosensor which was composed of hemoglobin (Hb)-DNA conjugate on nanoporous gold thin film (NPGF) for hydrogen peroxide (H2O2) detection.
Jinhee Jo, Jinho Yoon, Taek Lee, Hyeon-Yeol Cho, Ji-Young Lee, Jeong-Woo Choi   +5 more
doaj   +1 more source

DNA nucleotide-specific modulation of \mu A transverse edge currents through a metallic graphene nanoribbon with a nanopore

, 2011
We propose two-terminal devices for DNA sequencing which consist of a metallic graphene nanoribbon with zigzag edges (ZGNR) and a nanopore in its interior through which the DNA molecule is translocated.
Areshkin D., Areshkin D. A., Brandbyge M., Branislav K. Nikolić, Brey L., Cai J., Cervantes-Sodi F., Fyta M., Garaj S., Geim A. K., Hasan M. Z., He Y., Healy K., Huang S., Jia X., Kamal K. Saha, Krems M., Kunstmann J., Lagerqvist J., Marija Drndić, Merchant C. A., Meunier V., Nelson T., Postma H. W. C., Prasongkit J., Rungger I., Rycerz A., Saha K. K., Saha K. K., Schadt E. E., Schneider G. F., Strange M., Tao C., Taylor J., Tsutsui M., Venkatesan B. M., Weeks C., Yazyev O. V., Zwolak M., Zârbo L. P.   +39 more
core   +1 more source