Results 51 to 60 of about 65,340 (244)

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Electrochemical Aptasensor for Detection of Dopamine [PDF]

, 2020
This work presents a proof of concept of a novel, simple, and sensitive method of detection of dopamine, a neurotransmitter within the human brain. We propose a simple electrochemical method for the detection of dopamine using a dopamine-specific aptamer
Abu-Ali, Hisham, Davis, Frank, Nabok, Alexei, Ozkaya, Cansu, Walch, Nik   +4 more
core   +1 more source

Toward Personalized Stationary Chromatography Phases: Equipping Commercial Silica Phases with Selected Peptide‐Based Binding Domains to Tailor Affinity

Advanced Materials Interfaces, EarlyView.
The 7‐mer peptide motifs QFFLFFQ, QFFEFFQ, and QFQQSFF, known as good, medium, and poor binders for the photosensitizers m‐THPC and Chlorin E6 are covalently immobilized on commercial amino‐functionalized silica particles by inverse electron‐demand Diels‐Alder ligation.
Steffen A. Busche, Lukas D. Bangert, Raoul D. Brand, Tommy Kröger, Enrico Heyl, Hans G. Börner   +5 more
wiley   +1 more source

Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. [PDF]

, 2016
High titer, class-switched autoantibodies are a hallmark of systemic lupus erythematosus (SLE). Dysregulation of the interferon (IFN) pathway is observed in individuals with active SLE, although the association of specific autoantibodies with chemokine ...
Baechler, Emily C, Balboni, Imelda M, Diep, Vivian K, Haddon, D James, Hall, Drew A, Lee, Jung-Rok, Petri, Michelle, Price, Jordan V, Utz, Paul J, Wand, Hannah E, Wang, Shan X   +10 more
core   +2 more sources

Ultrathin Gold for Robust Multi‐Element Surface Plasmon Resonance Biosensing

Advanced Materials Interfaces, EarlyView.
This is a pioneering work where for the first time we applied recently synthesised ultrathin layer of gold for plasmonic biosensing that makes use of multi‐element architectures. This study solves the problem of stability of the multi‐element biosensors as well as demonstrates increased sensitivity achieved by utilising new additions to low‐dimension ...
Vasyl G. Kravets, Andrew Strudwick, Alexander N. Grigorenko   +2 more
wiley   +1 more source

Basics of DNA biosensors and cancer diagnosis

Artificial Cells, Nanomedicine, and Biotechnology, 2014
The human genome is exposed to mutations during the life cycle because of many types of changes in the DNA. Viruses, radiation, transposons, mutagenic chemicals, or any errors that happen during DNA replication or the meiotic process in the cell, may cause the mutation.
Nasrin Sohrabi, Abolfazl Akbarzadeh, Alireza Valizadeh, Samad Mussa Farkhani   +3 more
openaire   +3 more sources

On noise processes and limits of performance in biosensors [PDF]

, 2007
In this paper, we present a comprehensive stochastic model describing the measurement uncertainty, output signal, and limits of detection of affinity-based biosensors.
Hajimiri, Ali, Hassibi, Arjang, Vikalo, Haris   +2 more
core   +1 more source

Multiplexed Bio‐detection on an Interferometric Optical Waveguide Assembly

Advanced Materials Interfaces, EarlyView.
Multiplexed remote bio‐detection is demonstrated through an image conduit composed of 3012 individual cores and coated with interferometric layers. The proof of concept of biodetection is performed through the kinetic monitoring of two complementary DNA strands hybridization paving the way for applications in multiplex in situ biosensing, and ...
Oleksii Bratash, Rémi Courson, Laurent Malaquin, Thierry Leichle, Arnaud Buhot, Loïc Leroy, Elodie Engel   +6 more
wiley   +1 more source

Giant Magnetoresistive Biosensors for Time-Domain Magnetorelaxometry: A Theoretical Investigation and Progress Toward an Immunoassay. [PDF]

, 2017
Magnetorelaxometry (MRX) is a promising new biosensing technique for point-of-care diagnostics. Historically, magnetic sensors have been primarily used to monitor the stray field of magnetic nanoparticles bound to analytes of interest for immunoassays ...
Hall, Drew A, Huang, Chih-Cheng, Zhou, Xiahan   +2 more
core   +1 more source

Antibiotic‐Mediated Plasmonic‐Mie Resonance for Biosensing Applications on a Novel Silicon Nanopillar Metasurface

Advanced Materials Interfaces, EarlyView.
Unique nanopillar metasurfaces are fabricated for the purpose of sensitive detection to refractive index changes in the presence of gold nanoparticles. The addition of these nanoparticles to the surface of the silicon nanopillars is facilitated via a novel antibiotic‐mediated linker system to promote localized surface plasmon effects resulting from Mie
Jacob Waitkus, JaeWoo Park, Theodore Ndukaife, Sui Yang, Ke Du   +4 more
wiley   +1 more source