Results 151 to 160 of about 54,243 (194)

Lamin: guardian against DNA damage by transcription stress. [PDF]

Cardiovasc Res
Jahng JWS, Wu JC.
europepmc   +1 more source

Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity

Advanced NanoBiomed Research, EarlyView.
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu, Jing Chen, Ji Zhu, Lixin Ru, Dongxiao Zhang   +4 more
wiley   +1 more source

The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions

Angewandte Chemie, EarlyView.
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi, Jake Brill, Sanne Roumans, Amal Mathai, John D. Brennan, Yingfu Li   +5 more
wiley   +2 more sources

Extrachromosomal DNA and cancer: function, formation, and clinical implications. [PDF]

J Exp Clin Cancer Res
Wu Y, Rui R, Tian T, Zheng J, He S, Zhou L, Li X, Gong Y.   +7 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Loss of SeqA confers low-level fluoroquinolone resistance through transcriptional reprogramming and RpoS dependence in <i>E. coli</i>. [PDF]

AIMS Microbiol
Faraz A, Khan NA, Singh DK, Syed H, Joshi MC.   +4 more
europepmc   +1 more source

Base excision repair within structure-forming repeat sequences and its impact on cancer and other diseases. [PDF]

NAR Cancer
Cohen CB, Coombes MC, Merlo CP, Kontor CA, Meah R, Whitaker AM.   +5 more
europepmc   +1 more source

Structure of Bacillus subtilis Ku-mediated DNA synaptic complex. [PDF]

Nucleic Acids Res
Kim WJ, Kim J, Jo M, Kim Y, Kim MS.
europepmc   +1 more source

The Role of Integrated HBV DNA in the Quest for a Cure in HIV/HBV co-infection. [PDF]

Curr HIV/AIDS Rep
Mani M, Thio CL, Balagopal A.
europepmc   +1 more source

Hepatitis B viral DNA integration occurs within three days of infection and is enhanced by ATR inhibition. [PDF]

Tumour Virus Res
Li D, Wettengel JM, Ajoyan H, Ho V, Wu G, Bae S, Zhang H, Boldbaatar D, George J, Douglas MW, Tu T.   +10 more
europepmc   +1 more source