Results 271 to 280 of about 104,786 (306)
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DNA Double Strand Break Induction in Yeast
Radiation Protection Dosimetry, 2002The induction of DNA double strand breaks (DSBs) by accelerated heavy ions was systematically measured in diploid yeast cells. Particles were provided by the accelerators at GSI, Darmstadt, and HMI, Berlin. DNA was separated using pulsed field gel electrophoresis and the intensity of the largest bands used to determine the loss of molecular weight ...
J, Kiefer, R, Egenolf, S E, Ikpeme
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DksA and DNA double-strand break repair
Current Genetics, 2019We use genetic assays to suggest that transcription-coupled repair or new origin formation in Escherichia coli involves removal of RNAP to create an RNA primer for DNA synthesis. Transcription factor DksA was shown to play a role in numerous reactions involving RNA polymerase.
Kamila K. Myka, Max E. Gottesman
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Autoantibodies against DNA double-strand break repair proteins
Frontiers in Bioscience, 2001Autoantibodies against cellular components are commonly present in sera from patients with systemic rheumatic diseases and may play an important role in pathogenesis. The Ku protein was recognized 20 years ago as a major target of autoantibodies in a subset of Japanese patients with scleroderma-polymyositis overlap syndrome, and anti-Ku antibodies have
Y, Takeda, W S, Dynan
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Chromatin compartments at DNA double-stranded breaks
Cell Research, 2023Jaewon, Min, Jean, Gautier
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
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Asbestos and DNA double strand breaks.
Cancer research, 1999A radiosensitive DNA repair-deficient xrs-5 cell line was used to study asbestos cytotoxicity and DNA double strand breaks (DSBs). Although xrs-5 cells did not show any increase in sensitivity to chrysotile fibers in short-term (4-h) treatment when compared with wild-type CHO cells, longer-term exposure (24 h) gave significantly lower cell survival ...
R, Okayasu +4 more
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Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids
Nature Reviews Molecular Cell Biology, 2022Eva Petermann, Li Lan, Lee Zou
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Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Nature, 2016Zhi-Xin Huang +2 more
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