Results 41 to 50 of about 3,380,471 (308)

Monte Carlo Simulation-Based Calculations of Complex DNA Damage for Incidents of Environmental Ionizing Radiation Exposure

open access: yesApplied Sciences, 2021
In this paper, we present a useful Monte Carlo (MC)-based methodology that can be utilized to calculate the absorbed dose and the initial levels of complex DNA damage (such as double strand breaks-DSBs) in the case of an environmental ionizing radiation (
Spyridon A. Kalospyros   +7 more
doaj   +1 more source

Lectures on DNA Codes

open access: yesCoRR, 2014
For $q$-ary $n$-sequences, we develop the concept of similarity functions that can be used (for $q=4$) to model a thermodynamic similarity on DNA sequences. A similarity function is identified by the length of a longest common subsequence between two $q$-ary $n$-sequences. Codes based on similarity functions are called DNA codes.
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Security Improvement for OFDM-PON via DNA Extension Code and Chaotic Systems

open access: yesIEEE Access, 2020
In the paper, a deoxyribonucleic acid (DNA) extension code with 3-bit binary streams is proposed to encrypt the downlink data for orthogonal frequency division multiplexing passive optical network (OFDM-PON).
Tingwei Wu   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Apoptosis and DNA methylation [PDF]

open access: yes, 2011
Epigenetic mechanisms assist in maintaining gene expression patterns and cellular properties in developing and adult tissues. The molecular pathology of disease states frequently includes perturbation of DNA and histone methylation patterns, which can ...
Meng, Huan X   +18 more
core   +1 more source

BIOPHYSICAL BASES OF GENOME ORGANIZATION

open access: yesНаука и инновации в медицине, 2017
Aim - the analysis of nucleotide sequences of DNA molecules and the bases of the information storage with the help of DNA. Material and methods - the study is based on Markov chain theory and Bayesian Information Criterion. Results. Principles of genetic
AN N Volobuev   +2 more
doaj   +1 more source

Combinatorial constraint coding based on the EORS algorithm in DNA storage.

open access: yesPLoS ONE, 2021
The development of information technology has produced massive amounts of data, which has brought severe challenges to information storage. Traditional electronic storage media cannot keep up with the ever-increasing demand for data storage, but in its ...
Li Xiaoru, Guo Ling
doaj   +1 more source

Design of Nonbinary Error Correction Codes With a Maximum Run-Length Constraint to Correct a Single Insertion or Deletion Error for DNA Storage

open access: yesIEEE Access, 2021
Due to the advantages of high information densities and longevity, DNA storage systems have begun to attract a lot of attention. However, common obstacles to DNA storage are caused by insertion, deletion, and substitution errors occurring in DNA ...
Xiaozhou Lu, Sunghwan Kim
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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