Results 181 to 190 of about 736,909 (260)

Isoforms in action: The impact of transcript diversity in phenotype. [PDF]

open access: yesGenet Mol Biol
Mamede I   +4 more
europepmc   +1 more source

Highly Anisotropic Quasi‐Direct Organic Metal Halide Hybrids: A Platform for Polarization‐Sensitive Optoelectronics

open access: yesAdvanced Materials Technologies, EarlyView.
One‐dimensional C4N2H14PbBr4 is shown to have a quasi‐direct electronic band structure and strongly anisotropic transport with polarized broadband emission. A GW/Bethe–Salpeter excited‐state force formalism, supported by polarized Raman and temperature‐dependent photoluminescence, identifies low–frequency Pb–Br phonons that drive ultrafast exciton self‐
Rijan Karkee   +7 more
wiley   +1 more source

Editorial: Epigenetic modulation in cancer. [PDF]

open access: yesFront Oncol
Tricarico R, Mondal P, Cortellino S.
europepmc   +1 more source

Reconnaissance Peptide Labeling Grain Boundary of Chemically Grown MoS2 Polycrystalline Monolayer

open access: yesAdvanced Materials Technologies, EarlyView.
Self‐assembled peptides on substrates, through adsorption and aggregation, offer an alternative way to label grain boundaries in chemically grown single‐layer polycrystalline MoS2. During an early nucleation step, peptides preferentially bind to grain boundaries.
Linhao Sun, Jinhua Hu
wiley   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

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