Results 191 to 200 of about 736,909 (260)

Accurate prediction of candidate lncRNAs associated with DNA damage response based on gene expression patterns from graph neural networks. [PDF]

Bioinform Adv
Shah S, Wang L.
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Mitochondrial genome of <i>Cossura pygodactylata</i> Jones 1956 (Annelida: Sedentaria) from the White Sea. [PDF]

Mitochondrial DNA B Resour
Ezhova M, Bezmenova A, Emelianenko V, Zhadan A, Knorre D, Neretina T.   +5 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

The complete plastome sequence of <i>Amorphophallus allenii</i> sheds light on intrageneric phylogeny of <i>Amorphophallus</i>. [PDF]

Mitochondrial DNA B Resour
Shi H, Wang W, Qi Y, Gao P, Yang M, Zhao Y, Huang F, Liu J, Zhao J, Li L, Yu L.   +10 more
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Complete genome sequence of the endophytic <i>Pseudomonas bijieensis</i> BR-1-Y isolated from the roots of medicinal plant <i>Stemona japonica</i>. [PDF]

Microbiol Resour Announc
Zhang J, Li L, Dai H, Chen T, Du Y, Xie K, Yang X.   +6 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

The complete mitochondrial genome and phylogenetic position of the tubeworm <i>Serpula uschakovi</i> Kupriyanova 1999 (Annelida: Serpulidae). [PDF]

Mitochondrial DNA B Resour
Bao Q, Zheng R, Kupriyanova EK, Sun Y.
europepmc   +1 more source