Results 51 to 60 of about 127,811 (292)

DNA Switching Circuits Based on Binary Tree

open access: yesIEEE Access, 2021
Switching circuits provide an interesting strategy for modularization construction of digital computing. Multi-step reactions on DNA origami template are essentially the same as switching circuits.
Zhao Chen   +4 more
doaj   +1 more source

DNA Computing in Microreactors [PDF]

open access: yes, 2002
The goal of this research is to improve the programmability of DNA-based computers. Novel clockable microreactors can be connected in various ways to solve combinatorial optimisation problems, such as Maximum Clique or 3-SAT. This work demonstrates by construction how one micro-reactor design can be programmed optically to solve any instance of Maximum
Danny van Noort   +2 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

REPORT: ATIP02.054: DNA Computing Research Activities in Europe To: Distribution From: [PDF]

open access: yes, 2007
This report describes DNA Computing Research activities in Europe. A brief description of the activities of the different European groups conducting both theoretical and experimental research is provided as well as information on two European Consortium ...
Dna Computing Research
core  

DNA extraction from formalin-fixed tissue: new light from the Deep-Sea [PDF]

open access: yes, 2010
DNA samples were extracted from ethanol and formalin-fixed decapod crustacean tissue using a new method based on Tetramethylsilane (TMS)-Chelex. It is shown that neither an indigestible matrix of cross-linked protein nor soluble PCR inhibitors impede PCR
Thatje, S.   +14 more
core   +2 more sources

Enzymatic Weight Update Algorithm for DNA-Based Molecular Learning

open access: yesMolecules, 2019
Recent research in DNA nanotechnology has demonstrated that biological substrates can be used for computing at a molecular level. However, in vitro demonstrations of DNA computations use preprogrammed, rule-based methods which lack the adaptability that ...
Christina Baek   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

DNA as a vehicle for the self-assembly model of computing [PDF]

open access: yes, 1998
A DNA version of the self-assembly model of computing, feasible using currently available laboratory techniques, is proposed. Input signals are coded into unmethylated and methylated oligonucleotides which then hybridize with a backbone that contains ...
Conrad, M., Zauner, K.-P.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A DNA Computing Model for the Graph Vertex Coloring Problem Based on a Probe Graph

open access: yesEngineering, 2018
The biggest bottleneck in DNA computing is exponential explosion, in which the DNA molecules used as data in information processing grow exponentially with an increase of problem size.
Jin Xu   +4 more
doaj   +1 more source

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