Results 61 to 70 of about 3,749,303 (292)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
DNA as a vehicle for the self-assembly model of computing
, 1998 A DNA version of the self-assembly model of computing, feasible using currently available laboratory techniques, is proposed. Input signals are coded into unmethylated and methylated oligonucleotides which then hybridize with a backbone that contains ...
Conrad, M., Zauner, K.-P.
core +1 more source
Discover Applied SciencesThe systematic review provides insights into advancements in DNA (Deoxyribonucleic Acid) cryptography, with respect to its growing integration with cloud computing, the Internet of Things (IoT), and DNA computing environments, based on published peer ...
N. Nasurudeen Ahamed, Thangavel Murugan
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Matrix-Chain Multiplication Based on Combinatorial Allosteric DNA Strand Displacement
IEEE AccessDNA computing has gained widespread attention for leveraging the unique properties of DNA molecules to perform computational operations. As a fundamental tool for analyzing data and optimizing models, matrix operation plays an important role in intensive
Hengyan Guo +2 more
doaj +1 more source
Ribonuclease-Responsive DNA Nanoswitches
Cell Reports Physical Science, 2020 Summary: DNA has been used in the construction of dynamic DNA devices that can reconfigure in the presence of external stimuli. These nanodevices have found uses in fields ranging from biomedical to materials science applications.
Arun Richard Chandrasekaran +2 more
doaj +1 more source
Biologicalization of Smart Manufacturing Using DNA-Based Computing
Biomimetics, 2023 Smart manufacturing needs cognitive computing methods to make the relevant systems more intelligent and autonomous. In this respect, bio-inspired cognitive computing methods (i.e., biologicalization) can play a vital role.
Sharifu Ura, Lubna Zaman
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
International Journal of Intelligent Networks, 2021 With the rapid development of distributed system technologies, one of the biggest challenges facing the digital world is ensuring the security of sensitive and confidential data during transport and storage, which are considered the most critical ...
Fursan Thabit +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source