Results 61 to 70 of about 333,155 (283)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Scaling up DNA digital data storage by efficiently predicting DNA hybridisation using deep learning

open access: yesScientific Reports, 2021
Deoxyribonucleic acid (DNA) has shown great promise in enabling computational applications, most notably in the fields of DNA digital data storage and DNA computing.
David Buterez
doaj   +1 more source

DNA sequences classification and computation scheme based on the symmetry principle [PDF]

open access: yes, 2009
The DNA sequences containing multifarious novel symmetrical structure frequently play crucial role in how genomes work. Here we present a new scheme for understanding the structural features and potential mathematical rules of symmetrical DNA sequences ...
Wen-Yuan Qiu, Xiao-Gang Song
core   +1 more source

Inferring coarse-grain histone-DNA interaction potentials from high-resolution structures of the nucleosome

open access: yes, 2014
The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex.
Everaers, Ralf, Meyer, Sam
core   +3 more sources

Boosting Backward Search Throughput for FM-Index Using a Compressed Encoding [PDF]

open access: yes, 2019
The rapid development of DNA sequencing technologies has demanded for com- pressed data structures supporting fast pattern matching queries. FM-index is a widely-used compressed data structure that also supports fast pattern matching queries.
Alastruey-Benedé, Jesús   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Matrix-Chain Multiplication Based on Combinatorial Allosteric DNA Strand Displacement

open access: yesIEEE Access
DNA computing has gained widespread attention for leveraging the unique properties of DNA molecules to perform computational operations. As a fundamental tool for analyzing data and optimizing models, matrix operation plays an important role in intensive
Hengyan Guo   +2 more
doaj   +1 more source

Ribonuclease-Responsive DNA Nanoswitches

open access: yesCell Reports Physical Science, 2020
Summary: DNA has been used in the construction of dynamic DNA devices that can reconfigure in the presence of external stimuli. These nanodevices have found uses in fields ranging from biomedical to materials science applications.
Arun Richard Chandrasekaran   +2 more
doaj   +1 more source

Biologicalization of Smart Manufacturing Using DNA-Based Computing

open access: yesBiomimetics, 2023
Smart manufacturing needs cognitive computing methods to make the relevant systems more intelligent and autonomous. In this respect, bio-inspired cognitive computing methods (i.e., biologicalization) can play a vital role.
Sharifu Ura, Lubna Zaman
doaj   +1 more source

Improved Lower Bounds for Constant GC-Content DNA Codes

open access: yes, 2008
The design of large libraries of oligonucleotides having constant GC-content and satisfying Hamming distance constraints between oligonucleotides and their Watson-Crick complements is important in reducing hybridization errors in DNA computing, DNA ...
Chee, Yeow Meng, Ling, San
core   +2 more sources

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