Results 81 to 90 of about 333,155 (283)
Drip and Mate Operations Acting in Test Tube Systems and Tissue-like P systems
, 2009 The operations drip and mate considered in (mem)brane computing resemble the operations cut and recombination well known from DNA computing. We here consider sets of vesicles with multisets of objects on their outside membrane interacting by drip and ...
A. Păun +33 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Hardware-Accelerated Data Readout Platform Using Heterogeneous Computing for DNA Data Storage
Applied SciencesDNA data storage has emerged as a promising alternative to traditional storage media due to its high density and durability. However, large-scale DNA storage systems generate massive sequencing reads, posing substantial computational complexity and ...
Xiaopeng Gou +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Parallel Function Application on a DNA Substrate [PDF]
, 1996 In this paper I present a new model that employs a biological (specifically DNA -based) substrate for performing computation. Specifically, I describe strategies for performing parallel function application in the DNA-computing models described by ...
Blumberg, Andrew Justin
core +1 more source
, 2010 The electrical conduction properties of G4-DNA are investigated using a hybrid approach, which combines electronic structure calculations, molecular dynamics (MD) simulations, and the formulation of an effective tight-binding model Hamiltonian.
Cuniberti, Gianaurelio +4 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Neuromorphic Computing and EngineeringDNA and other biopolymers are being investigated as new computing substrates and alternative to silicon-based digital computers. However, the established top–down design of biomolecular interaction networks remains challenging and does not fully exploit ...
Tanmay Pandey +2 more
doaj +1 more source