Results 101 to 110 of about 3,749,303 (292)
Encoding Genetic and Structural Information in DNA Using Electric Field Gradients and Nuclear Spins
Intelligent ComputingNuclear electric resonance (NER) offers a method of controlling nuclear spins using electric field gradients (EFGs), which is a critical concept in quantum computing.
Yu Zheng, Quansheng Ren
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
In memoriam of Yurii Rogozhin [PDF]
Computer Science Journal of Moldova, 2019 November 13, 2019 would be the 70th birthday of Prof. Yurii Rogozhin. Dr. hab.~Yurii Rogozhin (November 13, 1949 $\dagger$ March 10, 2014) was a worldwide known computer scientist with diverse interests, ranged from finding small universal Turing ...
The staff of the Vladimir Andrunachievici Institute of Mathematics and Computer Science
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Accelerating DNA computing via freeze-thaw cycling. [PDF]
Sci Adv, 2023 Zhu Y +5 more
europepmc +1 more source
, 2008 In this excellent text, the reader is given a comprehensive introduction to the field of DNA computing. The book emphasizes computational methods to tackle central problems of DNA computing, such as controlling living cells, building patterns, and ...
Ignatova, Zoya +2 more
core
, 2013 DNA-based computing provides an alternative to solving optimization problems in graph theory. In this research, it is shown how DNA-based computing is used to find solutions to these problems, which involve logical thinking and are often NP hard complete.
Yong, Kian Yan
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