Results 161 to 170 of about 8,402,765 (253)

Analysis in Proceratophrys boiei genome illuminates the satellite DNA content in a frog from the Brazilian Atlantic forest. [PDF]

Front Genet, 2023
João Da Silva M, Gazoni T, Haddad CFB, Parise-Maltempi PP.   +3 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

DNA computation [PDF]

This is the first ever doctoral thesis in the field of DNA computation. The field has its roots in the late 1950s, when the Nobel laureate Richard Feynman first introduced the concept of computing at a molecular level. Feynman's visionary idea was only
Amos, Martyn
core  

The role of DNA content in shaping chromatin architecture and gene expression. [PDF]

Plant J
Barragán-Rosillo AC, Chávez Montes RA, Herrera-Estrella L.   +2 more
europepmc   +1 more source

Mastering DNA Content Estimation by Flow Cytometry as an Efficient Tool for Plant Breeding and Biodiversity Research. [PDF]

Methods Protoc, 2023
Fomicheva M, Domblides E.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Endoscopic liquid biopsies of gastric fluid in a large human patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer. [PDF]

Elife
Cadoná FC, Bartelli TF, Pelosof AG, Sztokfisz CZ, Bueno AP, Batista do Carmo Dos Santos L, Branco GP, Oliveira Dos Santos G, Nunes WA, Pintor FA, Lie Senda de Abrantes L, Defelicibus A, Gonzaga Vaz Coelho L, Leja M, In H, Li S, Hochster H, Coimbra FJF, Drummond R, Tojal Da Silva I, Chokshi RJ, Pasqualini R, Arap W, Nunes DN, Dias-Neto E.   +24 more
europepmc   +1 more source

Does Trophectoderm Mitochondrial DNA Content Affect Embryo Developmental and Implantation Potential? [PDF]

Int J Mol Sci, 2022
Lukaszuk K, Podolak A.
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Substantial structural variation and repetitive DNA content contribute to intraspecific plastid genome evolution. [PDF]

BMC Genomics
López-Caamal A, Gandee T, Galloway LF, Barnard-Kubow KB.   +3 more
europepmc   +1 more source