Results 1 to 10 of about 5,698,803 (355)

Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts

Journal of Nucleic Acids, 2010
DNA adducts play a central role in chemical carcinogenesis. The analysis of formation and repair of smoking-related DNA adducts remains particularly challenging as both smokers and nonsmokers exposed to smoke are repetitively under attack from complex ...
Bo Hang
doaj   +1 more source

DNA damage kinase signaling: checkpoint and repair at 30 years

EMBO Journal, 2019
From bacteria to mammalian cells, damaged DNA is sensed and targeted by DNA repair pathways. In eukaryotes, kinases play a central role in coordinating the DNA damage response.
Michael C. Lanz, Diego Dibitetto, M. Smolka   +2 more
semanticscholar   +1 more source

Dynamic Interplay between Cockayne Syndrome Protein B and Poly(ADP-Ribose) Polymerase 1 during Oxidative DNA Damage Repair [PDF]

, 2022
Robert J. Lake, Rabeya Bilkis, Hua-Ying Fan   +2 more
openalex   +1 more source

Obesity, DNA Damage, and Development of Obesity-Related Diseases

International Journal of Molecular Sciences, 2019
Obesity has been recognized to increase the risk of such diseases as cardiovascular diseases, diabetes, and cancer. It indicates that obesity can impact genome stability.
M. Włodarczyk, G. Nowicka
semanticscholar   +1 more source

The Antioxidant Potential of Commercial Manuka Honey from New Zealand—Biochemical and Cellular Studies

Current Issues in Molecular Biology
Manuka honey (MH) is considered a superfood mainly because of its various health-promoting properties, including its anti-cancer, anti-inflammatory, and clinically proven antibacterial properties.
Julia Kaźmierczak-Barańska, Bolesław T. Karwowski   +1 more
doaj   +1 more source

The central role of DNA damage in the ageing process

Nature, 2021
B. Schumacher, J. Pothof, J. Vijg, J. Hoeijmakers   +3 more
semanticscholar   +1 more source

mapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters

Bioinform., 2013
Motivation: Ancient DNA (aDNA) molecules in fossilized bones and teeth, coprolites, sediments, mummified specimens and museum collections represent fantastic sources of information for evolutionary biologists, revealing the agents of past epidemics and ...
Hákon Jónsson, A. Ginolhac, Mikkel Schubert, Philip L. F. Johnson, L. Orlando   +4 more
semanticscholar   +1 more source

Synergistic Genotoxic Effects of Gamma Rays and UVB Radiation on Human Blood

Antioxidants
Exposure to ionizing and non-ionizing radiation from environmental and clinical settings can significantly threaten genomic stability, especially when combined.
Angeliki Gkikoudi, Athanasia Adamopoulou, Despoina Diamadaki, Panagiotis Matsades, Ioannis Tzakakos, Sotiria Triantopoulou, Spyridon N. Vasilopoulos, Gina Manda, Georgia I. Terzoudi, Alexandros G. Georgakilas   +9 more
doaj   +1 more source

DNA damage and repair in age-related inflammation

Nature reviews. Immunology, 2022
Yang Zhao, M. Simon, A. Seluanov, V. Gorbunova   +3 more
semanticscholar   +1 more source

The Influence of (5′R)- and (5′S)-5′,8-Cyclo-2′-Deoxyadenosine on UDG and hAPE1 Activity. Tandem Lesions are the Base Excision Repair System’s Nightmare

Cells, 2019
DNA lesions are formed continuously in each living cell as a result of environmental factors, ionisation radiation, metabolic processes, etc. Most lesions are removed from the genome by the base excision repair system (BER).
Bolesław T. Karwowski
doaj   +1 more source