Results 211 to 220 of about 1,589,396 (359)

DNA damage-dependent mechanisms of ionizing radiation-induced cellular senescence. [PDF]

PeerJ
Guan J, Li T, Ma F, Wang N, Zhang H, Li J, Li J, Xu C, Liu Q.   +8 more
europepmc   +1 more source

The effect of 2-[(aminopropyl)amino] ethanethiol on fission-neutron-induced DNA damage and repair

, 1989
D.J. Grdina, Sigdestad Cp, PJ Dale, JM Perrin   +3 more
openalex   +1 more source

Oxidant-induced DNA damage of target cells. [PDF]

, 1988
Ingrid U. Schraufstätter, Paul A. Hyslop, Janis H. Jackson, Charles G. Cochrane   +3 more
openalex   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Lamin: guardian against DNA damage by transcription stress. [PDF]

Cardiovasc Res
Jahng JWS, Wu JC.
europepmc   +1 more source

Damage to the bases in DNA induced by stimulated human neutrophils. [PDF]

, 1989
Janis H. Jackson, Ewa Gajewski, Ingrid U. Schraufstätter, Paul A. Hyslop, Alfred F. Fuciarelli, Charles G. Cochrane, M. Dizdaroglu   +6 more
openalex   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

The interplay of DNA damage, epigenetics and tumour heterogeneity in driving cancer cell fitness. [PDF]

Nat Commun
Rouault CD, Charafe-Jauffret E, Ginestier C.   +2 more
europepmc   +1 more source