Results 231 to 240 of about 1,610,430 (355)

Application of bifurcation theory and siRNA-based control signal to restore the proper response of cancer cells to DNA damage

, 2016
Emilia Kozłowska, Krzysztof Puszyński
openalex   +1 more source

Activation of the ATR-mediated DNA Damage Response by the HIV-1 Viral Protein R [PDF]

, 2003
Mikhail Roshal, Baek Kim, Yonghong Zhu, Paul Nghiem, Vicente Planelles   +4 more
openalex   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

DNA damage response pathway is a promising therapeutic target for extrachromosomal DNA-positive tumours. [PDF]

Clin Transl Med
Tian C, Gan H.
europepmc   +1 more source

Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease.

, 2020
B Van Houten, A Sancar
openalex   +1 more source

A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage [PDF]

, 2009
François‐Michel Boisvert, Yun Wah Lam, Douglas Lamont, Angus I. Lamond   +3 more
openalex   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Imaging the time course of DNA damage response at a nonrepetitive endogenous locus. [PDF]

Cell Rep Methods
Rybczynski AT, Cottle WT, Chen PT, Kwon J, Shang T, Wang Y, Meneses P, Pangeni S, Park Y, Gavrilov M, Ha T.   +10 more
europepmc   +1 more source

The Checkpoint Clamp Activates Mec1 Kinase during Initiation of the DNA Damage Checkpoint [PDF]

, 2006
Jerzy Majka, Anita Niedziela‐Majka, Peter Burgers   +2 more
openalex   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source