Results 231 to 240 of about 1,589,396 (359)

Gliotoxin causes oxidative damage to plasmid and cellular DNA.

open access: hybrid, 1988
R.D. Eichner   +4 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

SLFN11, far from being limited to responding to cancer DNA damage. [PDF]

open access: yesClin Exp Med
Xiao H   +8 more
europepmc   +1 more source

Cellular responses to DNA damage.

open access: green, 1985
Graham C. Walker   +2 more
openalex   +1 more source

Restricted repair of aflatoxin B1Induced damage In α DNA of monkey cells [PDF]

open access: green, 1983
Steven A. Leadon   +2 more
openalex   +1 more source

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