Results 31 to 40 of about 328,318 (240)

Large-Scale de novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Over the past decades, remarkable progress on phosphoramidite chemistry-based large-scale de novo oligonucleotide synthesis has been achieved, enabling numerous novel and exciting applications.
Li-Fu Song   +8 more
doaj   +1 more source

Uncertainties in synthetic DNA-based data storage [PDF]

open access: yesNucleic Acids Research, 2021
Abstract Deoxyribonucleic acid (DNA) has evolved to be a naturally selected, robust biomacromolecule for gene information storage, and biological evolution and various diseases can find their origin in uncertainties in DNA-related processes (e.g. replication and expression).
Chengtao Xu   +3 more
openaire   +2 more sources

High capacity DNA data storage with variable-length Oligonucleotides using repeat accumulate code and hybrid mapping

open access: yesJournal of Biological Engineering, 2019
Background With the inherent high density and durable preservation, DNA has been recently recognized as a distinguished medium to store enormous data over millennia.
Yixin Wang   +5 more
doaj   +1 more source

DNA-Aeon provides flexible arithmetic coding for constraint adherence and error correction in DNA storage

open access: yesNature Communications, 2023
The extensive information capacity of DNA makes it an attractive alternative to traditional data storage. DNA-Aeon is a DNA data storage solution that can correct all error types commonly observed in DNA storage, while encoding data into sequences that ...
Marius Welzel   +7 more
doaj   +1 more source

Biotechnological tools boost the functional diversity of DNA-based data storage systems

open access: yesComputational and Structural Biotechnology Journal
DNA-based data storage has emerged as a groundbreaking solution to the growing demand for efficient, high-density, and long-term data storage. It is attracting many researchers’ attention, who are implementing functions such as random access, searching ...
Xiaoyuan Xu, Wen Wang, Zhi Ping
doaj   +1 more source

Biological constraint in digital data encoding: A DNA based approach for image representation

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics)
Digital data encoding is crucial for communication and data storage, but conventional techniques, such as ASCII and binary coding, have drawbacks in terms of processing speed and storage capacity.
Muhammad Rafi Muttaqin   +5 more
doaj   +1 more source

Adaptive coding for DNA storage with high storage density and low coverage

open access: yesnpj Systems Biology and Applications, 2022
The rapid development of information technology has generated substantial data, which urgently requires new storage media and storage methods. DNA, as a storage medium with high density, high durability, and ultra-long storage time characteristics, is ...
Ben Cao   +3 more
doaj   +1 more source

Mobile and Self‐Sustained Data Storage in an Extremophile Genomic DNA

open access: yesAdvanced Science, 2023
DNA has been pursued as a novel biomaterial for digital data storage. While large‐scale data storage and random access have been achieved in DNA oligonucleotide pools, repeated data accessing requires constant data replenishment, and these ...
Fajia Sun   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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