Results 51 to 60 of about 328,318 (240)

Current and emerging opportunities in biological medium‐based computing and digital data storage

Nano Select, 2022
Traditional storage methods have limitations and concerns regarding capacity, decay, and sustainability. These drawbacks can be mitigated by developing long‐term digital information storage systems using deoxyribonucleic acid (DNA), which are often ...
Devasier Bennet, Tuan Vo‐Dinh, Frederic Zenhausern   +2 more
doaj   +1 more source

Hidden Addressing Encoding for DNA Storage

Frontiers in Bioengineering and Biotechnology, 2022
DNA is a natural storage medium with the advantages of high storage density and long service life compared with traditional media. DNA storage can meet the current storage requirements for massive data.
Penghao Wang, Ziniu Mu, Lijun Sun, Shuqing Si, Bin Wang   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Coding for DNA data storage

, 2022
DNA has recently become an attractive medium for long-term data archive due to its extremely high density (zettabytes per gram), durable preservation and extremely low power consumption. Previous works have designed and implemented several prototypes for this emerging data storage technique where data was encoded, stored, and retrieved without errors ...
openaire   +2 more sources

Linked data storage using DNA origami nanostructures

Nature Communications
DNA-based storage is an alternative solution for archiving vast cold data. Its future development aims to meet the demands of hot data storage, which requires rapid random access and efficient data modification.
Chenhao Zhang, Mo Xie, Lianhui Wang, Chunhai Fan, Jie Chao   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient data reconstruction: The bottleneck of large-scale application of DNA storage

Cell Reports
Summary: Over the past decade, the rapid development of DNA synthesis and sequencing technologies has enabled preliminary use of DNA molecules for digital data storage, overcoming the capacity and persistence bottlenecks of silicon-based storage media ...
Ben Cao, Yanfen Zheng, Qi Shao, Zhenlu Liu, Lei Xie, Yunzhu Zhao, Bin Wang, Qiang Zhang, Xiaopeng Wei   +8 more
doaj   +1 more source