Results 41 to 50 of about 47,259 (168)

Eines moleculars en agricultura [PDF]

, 2010
Els marcadors moleculars són les eines utilitzades per l'ésser humà com a suport per a l'agricultura, i han representat un gran avenç en la millora genètica vegetal.
Monfort, Amparo
core  

Substrate‐Tight Graphene Transmembrane‐nanofluidic Devices

Small, EarlyView.
This study demonstrates that the covalent coupling of a pyrene layer to a silicon nitride substrate using silane and peptide chemistry increases the adhesion of graphene to the substrate and prevents the delamination of graphene. 76.2% of the devices with free‐standing graphene are successful devices for ion transport measurement in 0.1 M HCl ...
Xiaofang Kang, Buhang Chen, Erik P. van Geest, Wangyang Fu, Jianwei Gao, Luzhao Sun, Zhongfan Liu, Grégory F. Schneider   +7 more
wiley   +1 more source

Mitochondrial neurogastrointestinal encephalomyopathy: approaches to diagnosis and treatment [PDF]

, 2020
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disease caused by mutations in TYMP, the gene encoding for the enzyme thymidine phosphorylase.
Bax, BE
core   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Identificação de clones BAC com marcadores moleculares visando a integração de mapas físicos e genéticos. [PDF]

, 2014
Bibliotecas BAC (Cromossomo Artificial de Bactéria) têm sido muito utilizadas para suporte de trabalhos de mapeamento físico, clonagem posicional, mapeamento comparativo e estudos de evolução de genomas.
CAÇÃO, S. M. B., PEREIRA, L. F. P., SILVA, N. V., VIEIRA, L. G. E.   +3 more
core  

Quantification of Plasma and Urine Thymidine and 2'-Deoxyuridine by LC-MS/MS for the Pharmacodynamic Evaluation of Erythrocyte Encapsulated Thymidine Phosphorylase in Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy. [PDF]

, 2020
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare disorder caused by mutations in TYMP, leading to a deficiency in thymidine phosphorylase and a subsequent systemic accumulation of thymidine and 2'-deoxyuridine.
Antunes, NJ, Bax, BE, Blakely, EL, Fairbanks, LD, Hecht, M, Kalkan Uçar, S, Kipper, K, Levene, M, Schaefer, A   +8 more
core   +1 more source

BIEN: A biodiversity informatics ecosystem advancing open and reproducible workflows for plant observation, plot and trait data

Methods in Ecology and Evolution, EarlyView.
Abstract The rapid expansion of biodiversity data presents new opportunities to understand and forecast biosphere dynamics. However, disparate and dispersed data, taxonomic and geographic inconsistencies, pervasive quality issues, and a lack of reproducable workflows hinder synthesis, introduce biases and limit accurate assessment of biodiversity ...
Brian J. Enquist, Brad Boyle, Brian S. Maitner, Cory Merow, Ben S. Carlson, Xiao Feng, Gabriel M. Moulatlet, Erica A. Newman, Daniel S. Park, Michiel Pillet, Patrick R. Roehrdanz, Josep M. Serra‐Diaz, Rethvick S. Y. Babu, George G. C. Barbosa, Nathan Casler, John C. Donoghue II, Daniel Guaderrama, Rohith K. Sajja, Thomas L. P. Couvreur, Matthew B. Jones, Peter M. Jørgensen, Nathan J. B. Kraft, Pablo A. Marquet, Brian J. McGill, Nirav Merchant, Naia Morueta‐Holme, Danilo M. Neves, Ary Oliveira‐Filho, Robert K. Peet, Oliver Phillips, Brody Sandel, Mark Schildhauer, Irena Simova, Hans ter Steege, Jens‐Christian Svenning, Barbara Thiers, Cyrille Violle, Jan J. Wieringa, Susan K. Wiser   +38 more
wiley   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, EarlyView.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

Anaerobic co-digestion of acetate-rich with lignin-rich wastewater and the effect of hydrotalcite addition [PDF]

, 2016
The methane potential and biodegradability of different ratios of acetate and lignin-rich effluents from a neutral sulfite semi-chemical (NSSC) pulp mill were investigated.
Dahl Olli, Peka, Llorca Piqué, Jordi, Rodriguez Chiang, Lourdes Maria   +2 more
core   +2 more sources

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source